gamma-Cyclodextrin TCI C0869

Chemical Identity

Other names: Schardinger gamma-Dextrin · Cyclooctaamylose
CAS No.: 17465-86-0
PubChem: CID 5287407·SID 87565927
Formula: C48H80O40
Molecular weight: 1,297.13 g/mol
Purity: >99.0%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,38R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-5,10,15,20,25,30,35,40-octakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadeca
SMILES: C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(C(C8O)O)OC9C(OC(O2)C(C9O)O)CO)CO)CO)CO)CO)CO)CO)O)O)O
InChIKey: GDSRMADSINPKSL-HSEONFRVSA-N
MDL: MDL00009595

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TCI C0869 gamma-Cyclodextrin (CAS 17465-86-0) is a cyclic oligosaccharide built from eight alpha-1,4-linked glucose units, forming a truncated-cone structure with a hydrophilic exterior and a hydrophobic inner cavity. Its cavity is the largest among the common native cyclodextrins, allowing it to host relatively bulky guest molecules in inclusion complexes. Researchers use it to improve the aqueous solubility and stability of hydrophobic compounds, to encapsulate sensitive actives, and as a chiral selector in chromatographic and capillary electrophoresis separations. Available in 5g, 25g, and 100g packs, this hygroscopic white powder should be kept tightly sealed in a cool, dry place.

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Papaioannou et al. (2020). Dielectric behavior of gamma-cyclodextrin polymer and carboxymethyl gamma-cyclodextrin polymer cross-linked both by epichlorohydrin. Journal of Molecular Structure doi:10.1016/j.molstruc.2020.127831
(1990). 4904306 Separation and purification of gamma cyclodextrin. Biotechnology Advances doi:10.1016/0734-9750(90)90790-i
ÖRGÜL (2024). Comparison the solubility and dissolution rate effects of beta-cyclodextrin and gamma-cyclodextrin complexations of rosuvastatin calcium. Journal of Research in Pharmacy doi:10.29228/jrp.740

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.