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Description
TCI C0981 Cyclopropylamine (CAS 765-30-0) is a volatile primary amine bearing a strained three-membered ring, supplied in 5 mL and 25 mL bottles. Its nucleophilic amine reacts readily to form amides, sulfonamides, ureas, carbamates, and aromatic substitution products. The N-cyclopropyl motif is a well-known feature in medicinal chemistry, notably within quinolone antibacterial scaffolds. The material is highly flammable and corrosive, so handle it in a fume hood away from ignition sources and keep it tightly closed under cool storage.
Scientific References
Davidson et al. (1991). Inhibition by cyclopropylamine of the quinoprotein methylamine dehydrogenase is mechanism-based and causes covalent crosslinking of .alpha. and .beta. subunits. Biochemistrydoi:10.1021/bi00221a027
Manakhov et al. (2014). Cyclopropylamine plasma polymers deposited onto quartz crystal microbalance for biosensing application. physica status solidi (a)doi:10.1002/pssa.201431399
Mao et al. (2014). ChemInform Abstract: Asymmetric Synthesis of Cyclopropylamine Derivatives. ChemInformdoi:10.1002/chin.201439269
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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