TCI C0997 Cyclopropyl Cyanide (CAS 5500-21-0) is a compact aliphatic nitrile that delivers both a strained cyclopropane ring and a highly convertible cyano group. Hydrolysis affords cyclopropanecarboxylic acid, reduction gives cyclopropylmethylamine, and organometallic addition opens a direct route to cyclopropyl ketones. The cyclopropyl motif is widely used in medicinal chemistry to rigidify structures and fine-tune metabolic behaviour. AMI Scientific stocks 5 mL and 25 mL packs of this flammable liquid, which should be handled in a fume hood and stored tightly closed in a cool, well-ventilated place away from ignition sources.
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- Oh et al. (2002). Photodissociation of cyclopropyl cyanide at 193 nm. Chemical Physics Letters doi:10.1016/s0009-2614(02)01242-3
- Bizzocchi et al. (2008). Submillimetre-wave spectrum, 14N-hyperfine structure, and dipole moment of cyclopropyl cyanide. Journal of Molecular Spectroscopy doi:10.1016/j.jms.2008.02.009
- López et al. (2018). The reactivity of cyclopropyl cyanide in titan's atmosphere: a possible pre-biotic mechanism. Physical Chemistry Chemical Physics doi:10.1039/c7cp06911a
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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