TCI
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Description
TCI C1175 4-Chromanone (CAS 491-37-2) is an oxygen-containing heterocyclic building block featuring the chroman-4-one core found in many flavonoid-type natural products. Its ketone group at position 4 supports a broad range of transformations, including aldol condensation, reduction, and enamine or enolate chemistry. The compound is commonly used as a starting scaffold in medicinal chemistry programmes and structure–activity relationship studies. Available in 5 g and 25 g packs, it should be kept tightly closed in a cool, dry place away from heat and strong oxidising agents.
Scientific References
- Cloete et al. (2020). The evaluation of 1-tetralone and 4-chromanone derivatives as inhibitors of monoamine oxidase. Molecular Diversity doi:10.1007/s11030-020-10143-w
- Diana et al. (2021). Current developments in the synthesis of 4-chromanone-derived compounds. Organic & Biomolecular Chemistry doi:10.1039/d1ob01352a
- Huan (2011). Research progress of chromanone derivatives from Calophyllum. China Journal of Chinese Materia Medica doi:10.4268/cjcmm20110902
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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