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Description
TCI C1219 Methyl 2-Chloroacetoacetate (CAS 4755-81-1) is the methyl ester analogue of a widely used chlorinated β-ketoester building block. Its ester, ketone, and α-chloro functionalities allow straightforward access to thiazole, pyrazole, isoxazole, and pyridine ring systems. The α-chloro position acts as a convenient leaving group for nucleophiles such as amines, thiols, and thioamides. AMI Scientific offers this TCI reagent in 25 g and 250 g pack sizes for both exploratory synthesis and repeated preparative work.
