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Description
TCI C1294 4-Chloro-4'-fluorobutyrophenone is a fluorinated building block that combines an alkyl chloride chain with a para-fluorinated aryl ketone. The chloride is readily displaced by amines and other nucleophiles, while the carbonyl offers a second handle for reduction or ring formation. It is a well-known intermediate for constructing butyrophenone-type side chains in medicinal chemistry research. AMI Scientific offers this TCI reagent in a 25 g pack size suited to laboratory-scale synthesis and route optimisation.
