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Description
TCI C1305 3-Chloromethyl-5-nitrosalicylaldehyde is a densely functionalised aromatic building block bearing aldehyde, phenol, chloromethyl, and nitro groups. The adjacent aldehyde and phenol form the classic motif for Schiff base and salen ligand synthesis, while the chloromethyl group provides an alkylation handle for macrocycles and supported materials. The nitro group tunes ring electronics and can be reduced to an amine for further elaboration. AMI Scientific supplies this TCI reagent in 5 g and 25 g pack sizes for exploratory and preparative research.
