TCI C1436 N-Cyclohexylformamide (CAS 766-93-8) is a substituted formamide that serves as a convenient precursor to cyclohexyl isocyanide through dehydration. The resulting isocyanide is a key component in multicomponent reactions such as the Ugi and Passerini reactions, widely used in combinatorial and medicinal chemistry. The compound also functions as a formyl source and as an additive or ligand in selected catalytic systems. AMI Scientific supplies this TCI reagent in a 25 g laboratory package.
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- Deng et al. (1998). A Raman Spectroscopic Characterization of Bonding in the Complex of Horse Liver Alcohol Dehydrogenase with NADH and N-Cyclohexylformamide. Biochemistry doi:10.1021/bi981477e
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