TCI C1447 (1R,2R)-(-)-1,2-Cyclohexanediamine (CAS 20439-47-8) is an enantiopure trans vicinal diamine and a cornerstone chiral building block in asymmetric synthesis. Its two adjacent primary amines form a rigid bidentate donor set, ideal for salen ligands, Schiff bases, and transition metal complexes. It is equally valuable as the backbone of thiourea and squaramide organocatalysts. AMI Scientific supplies this TCI product in 5 g and 25 g packs; because the free diamine is basic and air-sensitive, handle it under the manufacturer's recommended conditions.
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- He et al. (2014). Synthesis, Characterization and Antitumor Activities of Cis-Chlorogenic Acid[(1R,2R)-1,2-Cyclohexanediamine] Platinum(II). Advanced Materials Research doi:10.4028/www.scientific.net/amr.884-885.593
- HATA et al. (1992). Synthesis, Structure and Antitumor Activity of a Water-Soluble Platinum Complex, (1R,3R,4R,5R)-(-)-Quinato(1R,2R-cyclohexanediamine)platinum(II).. Chemical and Pharmaceutical Bulletin doi:10.1248/cpb.40.1604
- YOON et al. (1998). ChemInform Abstract: (1R,2R)‐(‐)‐N,N′‐Bis (3,5‐di‐tert‐butylsalicylidene)‐1,2‐cyclohexanediamine: A Salen Ligand of Jacobsen′s Catalyst.. ChemInform doi:10.1002/chin.199812027
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