TCI C1467 Ethyl Chlorofluoroacetate is a halogenated acetate ester bearing both chlorine and fluorine at the alpha carbon. It is valued as a reagent for introducing monofluorinated carbon units into target molecules through alkylation, condensation, and cyclisation chemistry. The ester group can be further converted into acids, amides, or alcohols, giving flexibility across multi-step synthetic routes. AMI Scientific supplies this liquid reagent in original TCI packaging, and it should be handled in a fume hood with full personal protective equipment because haloacetate esters are strongly irritating.
TCI brochures (PDF)
- Fluorination Reagents, Fluorinated Building Blocks 2026-03-18 · p. 51
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- Li et al. (2021). Nickel‐Catalyzed Cross‐Coupling of Ethyl Chlorofluoroacetate with Aryl Bromides. Chemistry – An Asian Journal doi:10.1002/asia.202100348
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