TCI C1502 Methyl 2-Chlorobenzoate is the methyl ester of 2-chlorobenzoic acid, featuring a chlorine atom ortho to the ester group. The ester can be hydrolyzed, transesterified, reduced, or reacted with organometallic reagents, while the aromatic chlorine serves as a handle for palladium- or copper-catalyzed cross-coupling and Ullmann-type chemistry. This dual reactivity makes it an efficient precursor toward anthranilate derivatives, acridones, and other fused benzo systems in pharmaceutical and materials research. AMI Scientific supplies this TCI building block in a 25 g pack, and detailed specifications should be verified from the manufacturer's official documentation.
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- Montañez et al. (2010). Regioselectivity of methyl chlorobenzoate analogues with trimethylstannyl anions by radical nucleophilic substitution: theoretical and experimental study. New Journal of Chemistry doi:10.1039/b9nj00664h
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