TCI C1616 4'-Chloropropiophenone (CAS 6285-05-8) is a chlorinated aryl ketone that serves as a versatile non-heterocyclic building block for research synthesis. The carbonyl group supports reduction, organometallic addition, and alpha-functionalisation, while the aromatic chlorine offers a handle for transition-metal cross-coupling. It is typically used in laboratory-scale organic synthesis and as a precursor toward heterocyclic frameworks. AMI Scientific supplies this TCI reagent strictly for legitimate research use, and handling must follow the manufacturer's SDS together with institutional controlled-substance and chemical management policies.
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- Chen et al. (2014). 2-Bromo-3′-chloropropiophenone is a genotoxic impurity. Toxicology Letters doi:10.1016/j.toxlet.2014.06.682
- Sonneck et al. (2025). 3-Chloropropiophenone. IUCrData doi:10.1107/s2414314625003499
- Usui et al. (1998). Stereoselectivities in AgBF4-catalyzed and photoinduced phenyl-rearrangement of 2-chloropropiophenone. Tetrahedron Letters doi:10.1016/s0040-4039(98)02284-9
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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