Clindamycin Phosphate TCI C2257

Chemical Identity

Other names: Clindamycin 2-Dihydrogen Phosphate
CAS No.: 24729-96-2
PubChem: CID 443385·SID 87560447
Formula: C18H34ClN2O8PS
Molecular weight: 504.96 g/mol
Purity: >97.0%(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [(2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-[[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl] dihydrogen phosphate
SMILES: CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)OP(=O)(O)O)O)O)C(C)Cl
InChIKey: UFUVLHLTWXBHGZ-MGZQPHGTSA-N
MDL: MDL07793328

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Berat 5g 25g

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Dokumen Keamanan & Mutu

↓ Unduh SDS / MSDS (PDF resmi TCI)

CoA (Certificate of Analysis)

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TCI Clindamycin Phosphate is the phosphate ester salt of clindamycin, a lincosamide antibiotic that is a semi-synthetic derivative of lincomycin. The phosphate form is a prodrug: in biological systems, the phosphate group is hydrolysed to release active clindamycin. In the laboratory, the material serves as a reference compound for microbiology research, pharmaceutical formulation development, and drug quality analysis. It comes in 5g and 25g packs, so each laboratory can choose the quantity that suits the scale of its research.

Clindamycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It is mainly active against Gram-positive and anaerobic bacteria, so it is widely studied in the context of skin infections, soft tissue infections, and anaerobic infections. The phosphate ester is preferred because it dissolves in water more readily than clindamycin base. This makes it suitable for solutions, topical gels, and injectable preparations. Its prodrug behaviour also lets researchers study stability, enzymatic hydrolysis, and the release kinetics of the active compound.

In Indonesia, clindamycin phosphate is well known as the active ingredient in topical acne preparations and in injectable preparations. Pharmaceutical quality control laboratories, university pharmacy and microbiology departments, and formulation research groups use it as a reference material when they develop, test, or verify products containing clindamycin. The two pack sizes cover both small analytical work and larger formulation trials, so the compound is useful in teaching and in industry alike.

TCI brochures (PDF)

Antibiotic Ingredients for Drug-Resistant Pathogens 2026-10-01 · p. 1
Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 7
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 7

Related TCI products

Microbiology research: its activity against Gram-positive and anaerobic bacteria makes it a relevant reference compound for studying bacterial susceptibility and the mechanism of protein synthesis inhibition.
Pharmaceutical formulation development: because it dissolves in water better than clindamycin base, it suits work on solutions, topical gels, and injectable preparations.
Drug quality analysis: it serves as a reference compound when testing and verifying pharmaceutical products that contain clindamycin phosphate as the active ingredient.
Prodrug stability studies: the phosphate ester can be hydrolysed, so researchers can examine how stable the compound stays under different formulation and storage conditions.
Enzymatic hydrolysis and release kinetics research: the phosphate group is cleaved to release active clindamycin, so the compound fits studies of how fast and how completely the active drug is released.

Brand	TCI
CAS number	24729-96-2
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes	5g and 25g
Physical form	refer to the product label and Certificate of Analysis
Storage	follow the conditions stated on the TCI label and Safety Data Sheet

Store Clindamycin Phosphate under the conditions given on the TCI label and Safety Data Sheet. Keep it in its original tightly closed container, away from moisture, direct light, and heat. Reseal the container promptly after each use so the material is not exposed to air or humidity, because the phosphate ester can hydrolyse. Handle it in a clean, well-ventilated area and wear standard laboratory protection, including gloves, safety glasses, and a lab coat. Avoid inhaling dust and avoid contact with skin and eyes. Label any prepared solutions clearly, keep them away from food and drink, and dispose of waste according to local laboratory and environmental regulations.

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