5-Chloroquinoline TCI C2997

Name: TCI C2997 635-27-8 5-Chloroquinoline
Brand: TCI
SKU: TCI2510C299717912
Price: 1830150.0 IDR
Availability: InStock

Rp 1.830.150,00

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Berat 1g 5g

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Description

TCI C2997 5-Chloroquinoline, bearing CAS number 635-27-8, is an aromatic heterocyclic compound built on a quinoline framework — a pyridine ring fused to a benzene ring — with a chlorine atom occupying the five position. In synthetic laboratory work, this compound serves as a heterocyclic building block that supplies researchers with a ready-to-use quinoline core. The quinoline framework is one of the most frequently encountered structural motifs in bioactive compounds, ligands, and functional materials, so the availability of a chlorinated derivative with a defined substituent position is a substantial help in designing efficient and well-directed synthetic routes.

The characteristics that make this compound a preferred choice are the clarity of its substitution pattern together with the presence of a basic nitrogen atom in the ring. Because the chlorine is fixed at the fifth carbon, researchers can construct derivatives with controlled regiochemistry — an outcome that is difficult to achieve when chlorination is carried out in-house on unsubstituted quinoline. The ring nitrogen atom is weakly basic and capable of coordinating to metals, so the compound can be developed into a ligand or made to undergo reactions at the nitrogen atom, such as quaternary salt formation.

In Indonesian laboratories, this material is typically used in university and institutional research settings where organic synthesis, medicinal chemistry, and coordination chemistry work is carried out. It suits laboratories that build target molecules step by step from defined intermediates rather than preparing every fragment from scratch, and it fits routine bench-scale reaction work where a reliable, positionally defined quinoline starting material shortens a synthetic sequence and reduces the number of purification steps required.

Laboratory Applications

Heterocyclic building block synthesis — supplies a ready quinoline core with fixed substitution, letting researchers extend the scaffold without first performing their own chlorination step.
Medicinal chemistry route design — the quinoline motif appears frequently in bioactive compounds, making this a practical entry point for building and exploring derivative series.
Ligand preparation for coordination chemistry — the weakly basic ring nitrogen can coordinate to metal centres, allowing the compound to be elaborated into ligand structures.
Regiochemically controlled derivatisation — the chlorine fixed at the five position gives a defined handle for further transformation with predictable, controlled regiochemistry.
Nitrogen-centred reaction studies — the ring nitrogen supports reactions such as quaternary salt formation, useful in preparing modified quinoline species for functional materials work.

Specifications

Brand: TCI
CAS Number: 635-27-8
Chemical name: 5-Chloroquinoline
Product code: C2997
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Storage: store according to the manufacturer's instructions stated on the product label and safety data sheet

Handling and Storage

Store the container tightly closed in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials, following the storage conditions specified by the manufacturer on the product label and safety data sheet. Keep the material in its original supplier container, or in a compatible tightly sealed glass container clearly labelled with the chemical name and CAS number. Handle within a fume hood using appropriate personal protective equipment, including safety goggles, chemical-resistant gloves, and a laboratory coat. Avoid inhalation of vapours and direct contact with skin and eyes, close containers immediately after use, and dispose of residues and contaminated material in accordance with the applicable chemical waste procedures of your institution.