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Description
TCI C3015 Carteolol Hydrochloride is a pharmaceutical research reagent supplied as the hydrochloride salt of carteolol, a non-selective beta-blocker compound known for possessing intrinsic sympathomimetic activity. In the laboratory setting, this material serves as a reference compound for studying ligand interactions with beta-adrenergic receptors, as a comparison standard in the development of analytical methods, and as a subject of experimental pharmacological investigation. The product falls under the category of research reagents for experimental use, meaning its intended purpose is limited to scientific activity within the laboratory and it is not intended for treatment, prescription, or human consumption.
The property that makes this hydrochloride form widely preferred is its improved solubility in aqueous media compared with the corresponding free base, which makes the preparation of stock solutions for receptor assays, isolated tissue studies, and chromatographic method validation considerably more practical. As a solid salt, the compound is also relatively easy to weigh out accurately and tends to be more stable in storage than an oil or free-base form. Its carbostyril structure contributes a chromophore group that is useful for detection work, supporting the analytical handling of the material.
In Indonesian laboratories, this type of reagent is typically found in university pharmacology and pharmacy research groups, in analytical method development work, and in institutional research units engaged in experimental receptor and tissue studies. It is generally used in small, carefully measured quantities within controlled scientific protocols, with the understanding throughout that the material is designated strictly for experimental laboratory activity and not for any clinical, prescribing, or human-consumption purpose.
Laboratory Applications
- Beta-adrenergic receptor binding studies — the compound acts as a reference ligand for non-selective beta-blockade, allowing researchers to characterise receptor interaction behaviour under controlled experimental conditions.
- Analytical method development and validation — the salt form dissolves readily and can be weighed accurately, making it suitable as a comparison standard when establishing or verifying laboratory analytical procedures.
- Chromatographic method validation — the carbostyril structure provides a chromophore that assists detection, so the material supports the calibration and verification steps of chromatographic work.
- Isolated tissue pharmacology experiments — good aqueous solubility simplifies stock solution preparation, letting investigators study responses in isolated tissue preparations with reliable and reproducible dosing.
- Experimental pharmacology teaching and research — as a compound with documented intrinsic sympathomimetic activity, it serves as a study object for exploring beta-blocker pharmacological behaviour in research settings.
Specifications
- Brand: TCI
- CAS Number: 51781-21-6
- Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use)
- Physical form: solid salt (hydrochloride salt of carteolol)
- Pack sizes: available in standard TCI catalogue packaging; please confirm the pack size option when ordering
- Storage note: keep in the closed original container under the storage conditions stated on the product label and accompanying documentation
Handling and Storage
Store the container tightly closed in a cool, dry place, protected from moisture and direct light, following the conditions indicated on the product label and its accompanying documentation. Keep the material in its original supplier container, or transfer it to a clean, chemically compatible, well-sealed vessel that is clearly labelled with the compound name and CAS number. Handle the solid in a well-ventilated area using standard laboratory personal protective equipment, including a laboratory coat, gloves, and eye protection, and avoid generating or inhaling dust during weighing. Allow the container to reach room temperature before opening to limit moisture condensation. Because this is a research reagent for experimental use only, restrict handling to trained laboratory personnel and consult the relevant safety data sheet before use.
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