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TCI

CAS 6645-46-1

L-Carnitine Hydrochloride TCI C3058

L-Carnitine Hydrochloride TCI C3058
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Description

TCI C3058 L-Carnitine Hydrochloride is the hydrochloride salt form of L-carnitine, a naturally occurring quaternary ammonium compound that plays an essential role in cellular energy metabolism. Within the body, L-carnitine is responsible for transporting long-chain fatty acids across the mitochondrial membrane so that they can be oxidised to produce energy. As a laboratory reagent, this material is used in biochemical research, lipid metabolism studies, the preparation of cell culture media, and the development of analytical methods and nutritional formulations. The hydrochloride salt form is chosen because it is easier to handle than the free base, which is strongly hygroscopic.

The characteristics that make this hydrochloride form preferred are its better handling stability and its high solubility in water, allowing stock solutions to be prepared quickly for enzymatic assays as well as for cell culture work. As a chiral compound, the L form is the biologically active enantiomer, and using material with the correct configuration is decisive for the validity of metabolism research results. The zwitterionic structure of the molecule under neutral conditions gives it a distinctive polar character, which influences its chromatographic behaviour and the way it is separated and detected in analytical work.

In Indonesian laboratories, this reagent is typically found in university biochemistry and physiology laboratories, in nutrition and food science research groups, and in analytical laboratories that develop and validate testing methods. It is commonly used for routine teaching and research work involving lipid metabolism, for preparing supplemented culture media, and as a reference material when analytical procedures for carnitine content are being established or verified against samples.

Laboratory Applications

  • Lipid metabolism research — supplied as the biologically active L enantiomer, it allows fatty acid oxidation pathways to be studied with the correct stereochemistry, which is essential for valid metabolic results.
  • Enzymatic assay preparation — its high solubility in water means stock solutions can be prepared quickly and reliably for enzyme reaction mixtures without lengthy dissolution or heating steps.
  • Cell culture media supplementation — the material dissolves readily in aqueous media and is available in a stable salt form, making it convenient for preparing supplemented culture formulations for laboratory work.
  • Analytical method development — the distinctive polar, zwitterionic character of the molecule at neutral pH influences its chromatographic behaviour, making it suitable for developing and optimising separation and detection procedures.
  • Nutritional formulation studies — as a well-defined laboratory-grade carnitine source, it supports research and development work on nutritional formulations and on testing methods for carnitine content.

Specifications

  • Brand: TCI
  • CAS number: 6645-46-1
  • Category: Life Science > Biochemicals and Reagents > Amino Acids
  • Chemical form: hydrochloride salt of L-carnitine, the biologically active L enantiomer
  • Pack sizes: available in the standard packaging options offered for this catalogue item; please refer to the product listing for the sizes currently supplied
  • Storage: store according to the conditions stated on the manufacturer's label and safety data sheet

Handling and Storage

Store the container tightly closed in a cool, dry place, following the storage conditions given on the manufacturer's label and safety data sheet. Although the hydrochloride salt is easier to handle than the strongly hygroscopic free base, the material should still be protected from moisture, so keep it in its original tightly sealed container or in a well-closed glass container, and consider using a desiccator for opened packages. Weigh and transfer the powder using clean, dry spatulas and glassware to avoid contamination and moisture uptake. Handle the material in a well-ventilated area, wear a laboratory coat, gloves, and safety glasses, avoid generating dust, and wash hands thoroughly after use. Prepared aqueous stock solutions should be clearly labelled with the concentration and preparation date, stored appropriately, and used within a period validated for your own application.

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