4-Chloroquinoline 1-Oxide TCI C3682

Name: TCI C3682 4637-59-6 4-Chloroquinoline 1-Oxide
Brand: TCI
SKU: TCI2510C368218770
Price: 1653750.0 IDR
Availability: InStock

Rp 1.653.750,00

Sale Sold out

Shipping calculated at checkout.

Berat 250mg 1g

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.

Description

4-Chloroquinoline 1-Oxide, with CAS number 4637-59-6, is a heterocyclic quinoline compound that plays an important role as a building block in modern organic synthesis. It is a quinoline derivative carrying a chlorine atom at position 4 and an N-oxide group on the ring nitrogen, giving it a simple yet highly versatile structure. In the laboratory, this compound serves as a reactive intermediate for constructing more complex molecular frameworks, particularly in the synthesis of bioactive compounds, drug candidates, and functional materials.

The main characteristic that makes this compound a preferred choice is its distinctive reactivity as a quinoline N-oxide. The N-oxide group enhances the electrophilic character of the quinoline ring, facilitating nucleophilic attack, while the chlorine atom at position 4 can be substituted or further activated to extend the synthetic possibilities. The presence of the N-oxide group opens many chemical transformation pathways, such as nucleophilic substitution, reduction, and coupling reactions. This combination of features makes it a key reagent for developing heterocyclic compounds in both academic research laboratories and industrial laboratories.

In Indonesian laboratories, this compound is typically used as a synthetic intermediate in medicinal chemistry and organic research programs, where researchers build heterocyclic scaffolds for bioactive molecule discovery and materials development. Academic research groups commonly employ it when exploring new reaction routes for quinoline derivatives, while industrial laboratories use it as a reliable starting material for process development and the preparation of functional compounds. Its predictable reactivity and well-documented behavior allow chemists to incorporate it confidently into multi-step synthetic sequences.

Laboratory Applications

Nucleophilic substitution reactions: The chlorine atom at position 4 is readily displaced by nucleophiles, and the N-oxide group enhances ring electrophilicity, making this compound an efficient substrate for introducing diverse substituents onto the quinoline core.
Synthesis of bioactive compounds: As a versatile quinoline building block, it serves as a convenient starting point for constructing heterocyclic scaffolds that are frequently explored in medicinal chemistry and drug candidate development programs.
Reduction transformations: The N-oxide functionality can be selectively reduced to generate the corresponding quinoline derivatives, providing chemists with a controlled route to access different oxidation states of the ring system.
Coupling reactions: The activated quinoline framework supports transition-metal-mediated coupling strategies, allowing the attachment of aryl, heteroaryl, or alkenyl groups to build more complex molecular architectures.
Functional materials development: Its well-defined heterocyclic core makes it suitable for preparing compounds with tailored electronic or structural properties, supporting research into new functional materials in Indonesian laboratories.

Specifications

Brand: TCI; product code: C3682
CAS number: 4637-59-6
Chemical name: 4-Chloroquinoline 1-Oxide
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes and physical form: not specified in the reference product data
Storage note: store under conditions suitable for laboratory chemicals, following the container label and the safety data sheet

Handling and Storage

Store 4-Chloroquinoline 1-Oxide in a cool, dry, well-ventilated area, protected from moisture and direct sunlight. Keep the container tightly closed when not in use and store the material in its original packaging or an equivalent chemically compatible container. Always follow the instructions given on the label and in the safety data sheet provided by the supplier. Use appropriate personal protective equipment, including gloves, safety goggles, and a laboratory coat, and handle the compound in a fume hood where possible. Avoid inhalation of dust or vapors, avoid contact with skin and eyes, and keep the material away from incompatible substances and open flames. In case of spillage, follow standard laboratory spill procedures and dispose of waste in accordance with local regulations.