D-(+)-Fucose from TCI is a deoxy monosaccharide, specifically 6-deoxy-D-galactose. Its structure closely resembles D-galactose, except that the hydroxyl group on the sixth carbon is replaced by a hydrogen atom. In nature, the L-fucose enantiomer is far more common, mainly as a component of glycans on mammalian cells. The D form occurs in certain glycosides from plants and microorganisms. TCI lists this compound in its Glycoscience group. In the laboratory, D-(+)-Fucose is used as a carbohydrate standard, as a sugar analog in biological studies, and as a starting material for glycochemical synthesis.
The main appeal of D-(+)-Fucose is how closely it resembles more common sugars. Its core structure matches D-galactose but has no hydroxyl group at C-6, so researchers use it to test how much that group matters for protein binding, enzyme activity, or sugar transport. In microbiology and molecular biology, D-fucose is also known as a sugar analog that cells do not readily metabolize and that can affect how certain sugar operon systems are regulated. It is also an important comparison compound for L-fucose in studies of lectin and enzyme stereospecificity.
University research groups, biotechnology laboratories, and institutional research centres in Indonesia use D-(+)-Fucose in carbohydrate chemistry, glycobiology, and microbial genetics projects. Analytical laboratories can use it as a reference sugar when developing chromatographic methods for monosaccharides. Synthetic chemistry groups use it as a chiral building block for glycoside preparation. Because it is supplied under the TCI brand through AMI Scientific, laboratories can include it in research and teaching work alongside other reagents from the TCI glycoscience range.
TCI brochures (PDF)
- Carbohydrate reference standard: as a defined deoxy sugar, D-(+)-Fucose helps identify and compare monosaccharides in chromatographic and spectroscopic analysis of sugar mixtures.
- Structure–function studies of sugar binding: because it lacks only the C-6 hydroxyl of D-galactose, it shows how much that group contributes to protein, enzyme, or transporter recognition.
- Regulation of sugar operons in microbiology: since cells do not readily metabolize it, D-fucose is useful for studying how certain bacterial sugar operon systems are regulated.
- Stereospecificity studies of lectins and enzymes: as the enantiomer of the biologically common L-fucose, it is a comparison compound for testing how strictly lectins and enzymes distinguish D and L sugar forms.
- Glycochemical synthesis: D-(+)-Fucose is a starting material for preparing glycosides and related carbohydrate derivatives in synthetic glycochemistry research.
| Brand | TCI (product code D0049) |
|---|---|
| CAS number | 3615-37-0 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Glycoscience |
| Pack sizes | standard TCI pack sizes; please confirm availability with AMI Scientific |
| Physical form | — |
| Storage | follow the storage conditions on the TCI label and Safety Data Sheet |
- Chemical identity: D-(+)-Fucose (6-deoxy-D-galactose)
Store D-(+)-Fucose in its original, tightly closed TCI container in a cool, dry place away from moisture, heat, and direct sunlight, following the conditions on the product label and Safety Data Sheet. Reseal the container promptly after each use so the solid does not absorb humidity, which matters in Indonesia's tropical climate. Use clean, dry spatulas and glassware to avoid contamination. Follow general laboratory practice: wear gloves, safety glasses, and a lab coat, avoid creating or breathing in dust, and wash your hands after handling. Read the TCI Safety Data Sheet before use and dispose of waste according to local regulations.
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