3,4-Dihydroxyphenylacetic Acid, better known by its abbreviation DOPAC, is a phenylacetic acid with a catechol group (two adjacent hydroxyl groups) on its aromatic ring. In biology, DOPAC is known as one of the main metabolites of dopamine, so it is widely used in neurochemistry and pharmacology laboratories. In the chemistry laboratory, the compound also serves as a non-heterocyclic building block for synthesising catechol derivatives, esters, amides and other polyphenolic compounds built on a phenylacetic framework. This TCI product (catalogue D1283, CAS 102-32-9) supplies the compound for both analytical and synthetic work.
What sets DOPAC apart is its structure. The catechol group is redox-active and oxidises easily, so electrochemical detectors can pick up the compound with very high sensitivity. The carboxylic acid group adds a convenient reactive site for derivatisation. With both functions in one molecule, DOPAC works as an analytical standard as well as a synthetic starting material. Because it oxidises so readily, the quality of the starting material has a large effect on how accurate the results are. A well-characterised TCI product gives researchers a dependable reference point for quantitative measurements and for multi-step synthesis.
In Indonesia, DOPAC is relevant to pharmacology and neuroscience laboratories in faculties of medicine, pharmacy and biology that study dopamine metabolism and related neurochemical pathways. Organic and medicinal chemistry groups can also use it as a starting material when building catechol-containing compounds and polyphenol analogues. University research laboratories, analytical service units and teaching laboratories can all source this TCI-branded material through AMI Scientific for reproducible research and method development.
Related TCI products
- TCI V0052 776-99-8 3,4-Dimethoxyphenylacetone
- TCI B4800 29973-91-9 4-Benzyloxy-3-methoxyphenylacetic Acid
- TCI B4742 4547-57-3 4-Butoxyphenylacetic Acid
- TCI B4737 66916-99-2 2-Bromo-4-methoxyphenylacetic Acid
- TCI B4677 774-81-2 3-Bromo-4-methoxyphenylacetic Acid
- TCI B4674 1860-58-8 3-Benzyloxyphenylacetic Acid
- Dopamine metabolism studies: as a main metabolite of dopamine, DOPAC is a natural reference compound for neurochemistry and pharmacology research on dopaminergic pathways.
- Electrochemical detection standard: its redox-active catechol group gives very sensitive electrochemical detection, so it is well suited as a calibration and reference standard in analytical methods.
- Synthesis of catechol derivatives: the catechol ring on a phenylacetic framework makes it a useful non-heterocyclic building block for preparing new catechol-containing compounds.
- Ester and amide preparation: the carboxylic acid group gives a practical reactive site for esterification and amidation, letting researchers attach the DOPAC framework to other molecules.
- Polyphenol research: the combination of adjacent hydroxyl groups and a phenylacetic backbone supports synthesis and study of polyphenolic compounds with related structural features.
| Brand | TCI (catalogue number D1283) |
|---|---|
| CAS number | 102-32-9 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | available in TCI standard pack sizes; please confirm options with AMI Scientific |
| Physical form | refer to the TCI product specification and certificate of analysis |
| Storage | oxidation-sensitive catechol compound; store according to the TCI label and SDS |
DOPAC contains a catechol group that oxidises easily, so keep exposure to air, light and moisture to a minimum. Store the product in its original, tightly closed container in a cool, dry, well-ventilated place, following the storage conditions on the TCI label and safety data sheet. Reseal the container promptly after each use, and consider dispensing only the amount needed so the bulk material stays intact. Handle the compound with standard laboratory protective equipment, including gloves, safety glasses and a lab coat. Avoid creating or breathing in dust, and work in a fume hood or well-ventilated area. Keep it away from strong oxidising agents, and dispose of residues according to local regulations and institutional procedures.
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