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CAS 75714-60-2

(S)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl TCI D2802

(S)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl TCI D2802
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(S)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl is a chiral organic compound derived from the BINOL framework, widely used in asymmetric synthesis within modern chemical laboratories. This compound plays a crucial role as a chiral ligand and precursor for catalysts, enabling researchers to control the stereochemistry of reaction products with high efficiency. Its absolute configuration (S) provides the necessary chiral environment for the synthesis of target molecules with high enantioselectivity. The compound is essential in various organic synthesis applications, particularly in the development of asymmetric catalytic methods that underpin pharmaceutical and fine chemical industries.

The compound’s unique structural features, including bromo groups at positions 3,3' and methoxy groups at positions 2,2', make it a preferred choice for synthetic chemists. These functional groups offer additional sites for modification, allowing for further cross-coupling reactions to build more complex ligands. The methoxy groups also help maintain the axial chirality of the binaphthyl framework, ensuring the compound’s stereochemical integrity. Its stability and reactivity under controlled conditions further enhance its utility in laboratory settings.

In Indonesian laboratories, this compound is commonly used in research focused on asymmetric catalysis and chiral ligand development. It supports the work of chemists in creating enantiomerically pure compounds, which are critical in drug development and specialty chemical synthesis. Its availability and reliability make it a valuable asset in both academic and industrial research environments.

  • Asymmetric Catalysis: This compound is ideal for asymmetric catalytic reactions where precise control over stereochemistry is required, enabling the synthesis of enantiomerically pure compounds.
  • Chiral Ligand Development: Its chiral framework makes it a preferred choice for designing and synthesizing new chiral ligands used in catalytic processes.
  • Organic Synthesis Research: It supports a wide range of organic synthesis applications, particularly in the development of complex molecules with specific stereochemical configurations.
  • Pharmaceutical Compound Synthesis: The compound is used in the synthesis of pharmaceuticals where enantioselectivity is crucial for drug efficacy and safety.
  • Fine Chemical Production: It plays a role in the production of fine chemicals, where high purity and controlled stereochemistry are essential for industrial applications.

Brand TCI
CAS number 75714-60-2
Molecular formula
Purity
Category Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes Available in various quantities as per standard laboratory supply
Physical form Solid
Storage Store in a cool, dry place away from light

This compound should be stored in a cool, dry place, away from direct light and moisture to maintain its stability and purity. It is recommended to use airtight containers made of glass or high-density polyethylene to prevent contamination and degradation. Due to its chiral nature, it is important to handle the compound with care to avoid any physical or chemical alterations that may affect its stereochemical integrity. In laboratory settings, it should be kept in a well-ventilated area, and appropriate personal protective equipment should be worn when handling. Regular monitoring of storage conditions is advised to ensure optimal performance and safety during use.