(R)-3,3'-Dibromo-1,1'-bi-2-naphthol is a chiral compound widely used in asymmetric synthesis to produce molecules with specific stereochemistry and desired biological activity. This reagent plays a crucial role in organic chemistry laboratories, particularly in the development of enantiomerically pure compounds. Its application extends to pharmaceutical and biochemical research, where precise control over molecular structure is essential for drug development and functional molecule synthesis.
The compound’s unique structure, featuring two bromine atoms at the 3 and 3’ positions of the bi-2-naphthol framework, contributes to its high reactivity and compatibility with chiral catalysts. This structural feature allows it to effectively participate in asymmetric catalytic reactions, enhancing enantioselectivity. Its aromatic nature and functional groups make it a versatile tool for synthetic chemists aiming to achieve high stereocontrol in complex molecule synthesis.
In Indonesian laboratories, this compound is commonly used in research focused on organic chemistry, pharmacology, and biochemistry. It supports the development of new compounds with potential applications in medicine and industry. Many research institutions and universities in Indonesia rely on this material for advanced synthetic processes and experimental studies requiring high precision and selectivity.
- Asymmetric synthesis in pharmaceutical research due to its ability to produce enantiomerically pure compounds with high selectivity.
- Chiral ligand applications in catalytic reactions that require precise stereochemical control for drug molecule development.
- Organic synthesis of complex molecules where stereochemistry plays a critical role in determining biological activity.
- Biochemical studies involving chiral compounds that mimic natural molecules and interact with biological targets.
- Research in medicinal chemistry for the design and synthesis of novel therapeutic agents with improved efficacy and reduced side effects.
| Brand | TCI |
|---|---|
| CAS number | 111795-43-8 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents |
| Pack sizes | Available in various quantities as per standard chemical supply practices |
| Physical form | Solid |
| Storage | Store in a cool, dry place away from light and moisture |
This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to keep it in a sealed container to prevent moisture absorption and maintain its chemical integrity. Due to its brominated structure, it may react with certain materials, so it should be handled with care and stored in a compatible container such as glass or high-density polyethylene. Laboratory personnel should ensure proper ventilation when working with this compound and avoid exposure to open flames or high temperatures. Regular monitoring of storage conditions is advised to ensure the material remains stable and suitable for use in research applications.
—
