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Description
TCI D3866 N,N-Dimethylaniline is a classic tertiary aromatic amine consisting of a benzene ring bearing a dimethylamino group, prepared in a grade intended for biochemical research. The compound is one of the best-known reagents in organic chemistry and plays a triple role as a building block, an organic base, and a catalyst. The lone pair on the nitrogen is conjugated with the aromatic ring, which makes the ring strongly electron-rich and readily susceptible to electrophilic substitution at the para position. This property is precisely what makes it an important starting material for the synthesis of dyes and analytical reagents.
The characteristic that makes it so widely chosen is its moderate basicity combined with the fact that it is not excessively nucleophilic, because the nitrogen is already fully substituted. The compound is therefore effective as an acid scavenger in acylation and sulfonylation reactions without itself reacting with the substrate. In polymer chemistry, tertiary aromatic amines are well known as accelerators that speed up the decomposition of organic peroxides, so that radical polymerization can proceed at room temperature. In the analytical field, the reactivity of its ring is exploited in coupling reactions that yield coloured products.
In Indonesian laboratories, this reagent belongs to the Chemistry > Building Blocks > Non-Heterocyclic Building Blocks category and is typically kept as a standing item on the organic synthesis bench. It is drawn on for routine acylation and sulfonylation work, for the preparation of dye intermediates, and for polymer and adhesive formulation studies in academic, government, and industrial research settings. The biochemical research grade makes it suitable for work where a well-characterised, consistently supplied tertiary amine reagent is required.
Laboratory Applications
- Acid scavenging in acylation reactions: its moderate basicity binds the liberated acid effectively while the fully substituted nitrogen prevents unwanted attack on the substrate itself.
- Sulfonylation chemistry: it neutralises the acid generated during sulfonyl chloride couplings, keeping the reaction medium controlled without competing nucleophilically for the sulfonylating agent.
- Dye and pigment intermediate synthesis: the strongly electron-rich ring undergoes electrophilic substitution readily at the para position, giving the coupling reactivity that dye chemistry depends upon.
- Room-temperature radical polymerization: as a tertiary aromatic amine accelerator it promotes decomposition of organic peroxides, allowing cure and polymerization to proceed without external heating.
- Colorimetric analytical reagent preparation: the reactive aromatic ring participates in coupling reactions that generate coloured products, making it useful in the formulation of analytical detection systems.
Specifications
- Brand: TCI
- CAS number: 121-69-7
- Catalogue number: D3866
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Grade: for Biochemical Research
- Pack sizes: available in the standard TCI catalogue pack sizes; please confirm the size required when ordering
- Storage: store in a tightly closed container in a cool, dark, well-ventilated place
Handling and Storage
Store the container tightly closed in a cool, dark, and well-ventilated area, away from heat, ignition sources, and direct sunlight, and separated from strong oxidising agents and acids. Keep the material in its original supplier packaging or in a compatible, clearly labelled, chemically resistant container, and reseal it immediately after each use to limit exposure to air and moisture. As with all aromatic amines, handle the compound in a functioning fume hood and wear appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, and a laboratory coat. Avoid inhalation of vapours and any contact with skin or eyes, use compatible transfer tools, and manage residues and empty packaging in accordance with your institution's chemical waste procedures. Always consult the manufacturer's safety data sheet before first use.
![N,N-Dimethylaniline [for Biochemical Research] (CAS 121-69-7) - TCI D3866 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510D3866.jpg?v=1769141923&width=1946)
![N,N-Dimethylaniline [for Biochemical Research] (CAS 121-69-7) - TCI D3866 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510D3866.jpg?v=1769141923&width=1445)
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