Deferoxamine Mesylate TCI D4245

Name: TCI D4245 138-14-7 Deferoxamine Mesylate
Brand: TCI
SKU: TCI2510D424524788
Price: 3777900.0 IDR
Availability: InStock

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Berat 100mg

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Description

TCI D4245 Deferoxamine Mesylate (CAS 138-14-7) is the mesylate salt of deferoxamine, a hydroxamate siderophore of microbial origin that is widely known as an iron chelator with exceptionally high affinity. In the laboratory setting, this compound serves as a standard reagent for selectively binding iron(III) ions out of solutions, culture media, and biochemical assay systems. Its ability to form highly stable complexes makes it an important tool for researchers who need to control iron availability within an experiment, whether the work concerns iron metabolism, oxidative stress, or iron-dependent mechanisms of cell death.

The property that makes deferoxamine mesylate such a frequent choice is the set of three hydroxamate groups along its chain, which act together to form a hexadentate bond enveloping a single iron(III) ion. This binding is both very strong and highly selective, so free iron can be drawn out of a system without substantially disturbing other metal ions at the concentrations normally used in practice. The mesylate salt form provides good solubility in water, a practical advantage because stock solutions can be prepared without resorting to organic solvents. Beyond its role as a chelator, the compound is also valued for the reproducibility it brings to iron-restriction work.

In Indonesian laboratories, this material is typically handled in university research groups, biochemistry and molecular biology facilities, and analytical or applied research units that study iron handling in biological systems. It is usually prepared as an aqueous stock solution and then diluted into working buffers, culture media, or assay mixtures according to the protocol in use. Because it is supplied as a defined TCI catalogue reagent, it fits naturally into method development and routine repeat experiments where consistency between batches matters.

Laboratory Applications

Iron(III) sequestration from solutions and buffers: the hexadentate hydroxamate binding removes free iron with high affinity, giving researchers a defined iron-depleted starting condition for downstream measurements.
Iron metabolism studies: because the compound restricts iron availability selectively, it allows investigators to observe how a biological system responds when accessible iron is limited rather than absent by design.
Oxidative stress research: by binding free iron(III) tightly, deferoxamine mesylate helps distinguish iron-dependent oxidative processes from those that proceed independently of available iron.
Iron-dependent cell death mechanism work: controlled chelation lets researchers test whether an observed cell death pathway genuinely requires accessible iron in the experimental system under study.
Culture medium and biochemical assay conditioning: the good aqueous solubility of the mesylate salt means iron can be chelated in media or assay mixtures without introducing organic solvents that might perturb the system.

Specifications

Brand: TCI (catalogue number D4245)
CAS number: 138-14-7
Category: Chemistry > Synthetic Reagents > Chelation/Complexation Compounds
Chemical identity: mesylate salt of deferoxamine, a microbial hydroxamate siderophore
Solubility: good solubility in water; aqueous stock solutions can be prepared without organic solvents
Pack sizes and storage conditions: as supplied and specified by TCI for this catalogue item

Handling and Storage

Store the container tightly closed in a cool, dry place away from direct sunlight, moisture, and sources of heat, and follow the storage conditions stated by TCI on the product label for this catalogue item. Keep the material in its original supplier container, or in a clean, well-sealed, chemically compatible vessel that is clearly labelled if portions are transferred. Prepare aqueous stock solutions with clean glassware or plasticware and appropriate grade water, and handle the compound inside a fume hood or a well-ventilated work area. Wear a laboratory coat, safety glasses, and suitable gloves, avoid generating or inhaling dust when weighing the solid, and consult the manufacturer's safety data sheet before first use and before disposal of residues.