TCI
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Description
TCI D4279, CAS 14919-49-4, is 3,4'-Dihydroxyflavone, a flavonoid compound belonging to the phenylpropanoids and aromatic polyketides group within the life science biochemicals and reagents category. The molecule carries a classic flavone framework — a 2-phenylchromen-4-one system — bearing hydroxyl groups at position 3 on the C ring and position 4' on the B ring. As a laboratory reagent, flavone compounds with such a clearly defined hydroxylation pattern are widely used as reference materials, model substrates, and test compounds in biochemical and food science research.
The property that makes this compound a preferred choice is its specific hydroxyl substitution pattern. The hydroxyl group at position 3 sits adjacent to the carbonyl at position 4, forming an arrangement capable of participating in metal ion chelation and contributing to the antioxidant behaviour extensively studied across the flavonol class. The hydroxyl at position 4' on the B ring, meanwhile, influences the electron distribution and the spectroscopic character of the molecule. The conjugated flavone system gives a characteristic ultraviolet absorption, so the compound is readily detected in liquid chromatography analysis using UV or diode array detectors.
This structural clarity, combined with a defined substitution pattern, makes the material practical for routine work in Indonesian laboratories. It is typically handled in university and institutional research laboratories, food science groups, and biochemical laboratories that require a well-characterised flavone as a comparison standard or as a model compound in method development. Because the compound is supplied as a defined single substance, it fits analytical and preparative work where the identity of the flavone reference must be unambiguous.
Laboratory Applications
- Reference standard in chromatographic analysis — the defined flavone structure and characteristic ultraviolet absorption allow reliable peak identification and retention comparison on liquid chromatography systems fitted with UV or diode array detection.
- Model substrate in biochemical research — the classic 2-phenylchromen-4-on framework with known hydroxyl positions makes the molecule useful for studying how flavone structure relates to observed biochemical behaviour.
- Antioxidant behaviour studies — the 3-hydroxyl adjacent to the 4-carbonyl forms an arrangement associated with the antioxidant behaviour widely investigated in the flavonol class of compounds.
- Metal ion chelation investigations — the neighbouring hydroxyl and carbonyl arrangement can participate in chelating metal ions, providing a defined system for laboratory studies of flavonoid–metal interaction.
- Food science research work — as a test compound with a clearly known hydroxylation pattern, it serves as a comparison material in food science laboratories examining flavonoid components and their analytical determination.
Specifications
- Brand: TCI
- CAS number: 14919-49-4
- Chemical name: 3,4'-Dihydroxyflavone
- Category: Life Science > Biochemicals and Reagents > Phenylpropanoids, Aromatic Polyketides
- Pack sizes: available in standard TCI research packaging; please confirm the pack size options when ordering
- Storage: store according to the conditions stated on the manufacturer's label and safety data sheet
Handling and Storage
Store the container tightly closed in a cool, dry, and well-ventilated area, away from direct sunlight, heat, and sources of ignition, and follow the storage conditions given on the manufacturer's label and safety data sheet. Keep the material in its original container or in a suitable tightly sealed glass or chemically compatible vessel, clearly labelled and protected from moisture. Handle in a laboratory setting with adequate ventilation, preferably in a fume hood, and wear appropriate personal protective equipment including a laboratory coat, safety glasses, and chemical-resistant gloves. Avoid generating dust, avoid contact with skin and eyes, and wash hands thoroughly after handling. Consult the safety data sheet before use and dispose of residues in accordance with applicable laboratory waste procedures.
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