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TCI

CAS 443-86-7

3-Fluoro-2-methylaniline TCI F0526

3-Fluoro-2-methylaniline TCI F0526

Chemical Identity

Other names
2-Amino-6-fluorotoluene · 3-Fluoro-o-toluidine
CAS No.
443-86-7
PubChem
CID 285553·SID 87558095
Formula
C7H8FN
Molecular weight
125.15 g/mol
Purity
>98.0%(GC)(T)
Reference databases
ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
3-fluoro-2-methylaniline
SMILES
CC1=C(C=CC=C1F)N
InChIKey
SLDLVGFPFFLYBM-UHFFFAOYSA-N
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3-Fluoro-2-methylaniline is a chemical compound widely used in organic synthesis reactions within laboratory settings. It belongs to the category of fluorinated building blocks and is valued for its ability to participate in various chemical transformations. This compound features an aromatic ring with both fluorine and methyl substituents, making it a versatile reagent for synthetic chemists. Its structural complexity allows it to serve as a key intermediate in the development of complex molecules. Due to its reactivity, it is frequently employed in research involving nucleophilic substitution, condensation, and other organic reaction mechanisms.

The compound’s chemical properties make it a preferred choice for researchers seeking a flexible and reactive building block. It exhibits stability under certain conditions, yet remains sensitive to oxidation and light exposure, which requires careful handling. Its ability to form various derivatives and its compatibility with a range of reagents make it highly adaptable in synthetic pathways. The presence of fluorine in its structure also influences its reactivity and solubility, which are critical factors in its application. These characteristics make it a valuable tool for chemists working on drug development and industrial chemical synthesis.

In Indonesian laboratories, 3-Fluoro-2-methylaniline is commonly used in organic chemistry research, particularly in the development of pharmaceutical compounds, industrial chemicals, and complex reaction intermediates. Its availability in small pack sizes, such as 5 grams, facilitates its use in both academic and industrial research settings. Researchers in Indonesia rely on this compound for its reliability and performance in a variety of synthetic processes, making it an essential component of their chemical toolkit.

TCI brochures (PDF)

  • Organic synthesis research benefits from 3-Fluoro-2-methylaniline due to its reactivity and ability to form diverse derivatives, making it ideal for synthesizing complex molecules.
  • Pharmaceutical development utilizes this compound as a building block for creating drug candidates, leveraging its structural versatility and chemical stability.
  • Industrial chemical production incorporates this material for its role in creating specialized compounds used in various manufacturing processes.
  • Academic research in chemistry relies on this compound for its role in teaching and experimental studies involving fluorinated building blocks.
  • Complex reaction intermediates are often synthesized using this compound because of its ability to participate in multiple reaction types, enhancing synthetic flexibility.

Brand TCI
CAS number 443-86-7
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Fluorinated Building Blocks
Pack sizes 5 grams
Physical form Solid
Storage Store in a cool, dark place away from light and oxidizing agents

3-Fluoro-2-methylaniline should be stored in a cool, dark environment to prevent degradation due to light exposure. It is recommended to keep the compound in a tightly sealed container to minimize exposure to air and moisture. Suitable storage containers include glass or high-density polyethylene vessels that are resistant to chemical reactions. Due to its sensitivity to oxidation, it is important to avoid contact with strong oxidizing agents. In laboratory settings, proper ventilation and personal protective equipment should be used when handling this compound to ensure safety. Regular monitoring of storage conditions is advised to maintain the compound's integrity and effectiveness for research applications.

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