[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-beta-homoleucine TCI F1268

Chemical Identity

Other names: Fmoc-beta-Homoleu-OH · Fmoc-L-beta-homoleucine · (S)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-5-methylhexanoic Acid
CAS No.: 193887-44-4
Formula: C22H25NO4
Molecular weight: 367.45 g/mol
Purity: >96.0%(T)(HPLC)
Storage: 0-10°C

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-5-methylhexanoic acid
SMILES: CC(C)CC(CC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChIKey: YLVSABQQLLRFIJ-HNNXBMFYSA-N
MDL: MDL01863059
PubChem: CID 2761527

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(9H-Fluoren-9-ylmethoxy)carbonyl]-L-beta-homoleucine is a chemical compound widely used in peptide synthesis and biochemical research. This compound plays a crucial role in the construction of complex molecules with specific biological activities, such as synthetic peptides or protein analogs. In laboratory settings, it serves as a key component in coupling reactions, particularly within Fmoc (Fluorenylmethyloxycarbonyl) peptide synthesis strategies. Its application is essential for the controlled formation of peptide chains, making it indispensable in modern chemical biology workflows.

The compound is valued for its stable chemical structure and moderate reactivity, which allow it to participate effectively in a variety of chemical reactions. One of its most notable properties is its ability to form bonds with amino groups at the terminus of peptides, enabling precise and controlled chain elongation. This characteristic makes it highly suitable for applications requiring high specificity and accuracy, such as in pharmaceutical and biotechnological research. Its reliability and consistency in performance are key factors in its popularity among researchers.

In Indonesian laboratories, this compound is extensively used in drug development, protein modification, and molecular interaction studies. Researchers from academic institutions and industries frequently rely on it for experiments that demand precision and reproducibility in chemical synthesis. Its versatility and effectiveness make it a preferred choice for advanced biochemical investigations.

Peptide Synthesis: This compound is ideal for Fmoc-based peptide synthesis due to its ability to form stable amide bonds with amino groups, enabling the controlled elongation of peptide chains.
Drug Development: It is commonly used in the synthesis of bioactive peptides and protein analogs, supporting the creation of compounds with therapeutic potential.
Molecular Interactions: Its role in forming specific chemical bonds makes it suitable for studying molecular interactions in biochemical systems.
Protein Modification: It facilitates the modification of proteins by enabling the attachment of functional groups to specific sites, enhancing the study of protein behavior.
Biochemical Research: Its stability and reactivity make it a valuable tool in various biochemical experiments requiring precise chemical reactions.

Brand	TCI
CAS number	193887-44-4
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid (as per standard chemical product form)
Storage	Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and air. Due to its chemical nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. Avoid contact with skin and eyes, and ensure proper ventilation when working with the compound. It is important to follow standard laboratory safety protocols to ensure safe handling and storage. Always store the compound in a designated chemical storage area to minimize risks and ensure compliance with safety regulations.

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