Fmoc-Glu-OtBu TCI F1318

Chemical Identity

Other names: Fmoc-L-glutamic Acid 1-tert-Butyl Ester · (S)-4-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-5-(tert-butoxy)-5-oxopentanoic Acid
CAS No.: 84793-07-7
Formula: C24H27NO6
Molecular weight: 425.48 g/mol
Purity: >98.0%(HPLC)(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
SMILES: CC(C)(C)OC(=O)C(CCC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChIKey: GOPWHXPXSPIIQZ-FQEVSTJZSA-N
MDL: MDL00065648
PubChem: CID 7017912

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TCI F1318, also known as Fmoc-Glu-OtBu with CAS number 84793-07-7, is a chemical compound widely used in peptide synthesis. This compound is a protected form of glutamic acid, featuring the Fmoc (9-fluorenylmethyloxycarbonyl) group and the OtBu (tert-butoxycarbonyl) group. It plays a crucial role in chemical biology and peptide chemistry by enabling the controlled synthesis of complex peptide structures. Its unique chemical properties make it an essential tool for researchers working in various scientific disciplines.

The stability and controlled reactivity of Fmoc-Glu-OtBu make it a preferred choice in laboratory settings. The Fmoc group allows for precise coupling and deprotection steps during peptide synthesis, while the OtBu group provides temporary stability during the reaction process. These properties ensure that the compound remains chemically inert until the desired reaction conditions are met. This controlled behavior simplifies the synthesis of peptides with high structural fidelity and functional accuracy.

In Indonesian laboratories, Fmoc-Glu-OtBu is commonly used in peptide research, including drug development, biological analysis, and biomedical studies. Its role in creating custom peptides with specific sequences and functions makes it a valuable resource for both academic and industrial research. As a key component in peptide synthesis, it supports a wide range of applications that require precise chemical manipulation and controlled reaction environments.

Peptide Synthesis: Fmoc-Glu-OtBu is ideal for solid-phase peptide synthesis due to its controlled reactivity and stability during coupling reactions.
Drug Development: This compound is used in the synthesis of therapeutic peptides, enabling the creation of targeted drug molecules with specific biological activities.
Biological Analysis: It supports the production of peptides for use in assays and diagnostic tests, aiding in the study of biological processes and molecular interactions.
Biomedical Research: Fmoc-Glu-OtBu is essential for developing peptides used in regenerative medicine and therapeutic applications, contributing to advancements in biotechnology.
Academic Research: Its versatility makes it a preferred choice for researchers exploring new peptide structures and functions in molecular biology and chemistry.

Brand	TCI
CAS number	84793-07-7
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	Available in various quantities as per standard supplier offerings
Physical form	Solid powder
Storage	Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its reactivity, it should be handled with care in a well-ventilated laboratory setting. Avoid contact with incompatible substances and ensure proper personal protective equipment is used during handling. The compound is generally stable under standard laboratory conditions when stored correctly. Always follow standard safety protocols when working with chemical reagents to ensure a safe and controlled environment.

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