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Description
TCI G0165 Guanidine Phosphate is the salt formed from the reaction of guanidine with phosphoric acid, supplied as a white crystalline solid that is straightforward to measure out on the bench. It is classified as a non-heterocyclic building block because its main task is to donate the guanidino group — one of the most basic fragments in organic chemistry — into the framework of a target molecule. For synthetic researchers, the compound serves as a guanidine source that is far easier to handle than free guanidine, so it can be stored more safely, weighed repeatedly, and introduced into a reaction sequence without complicated special handling.
The characteristic that makes this material a preferred choice is its stability in salt form. Free guanidine is strongly basic and aggressive toward both carbon dioxide and atmospheric moisture, whereas its phosphate salt is far milder and can be kept for long periods without loss of quality. The phosphate anion brings its own advantages as well: it plays a role in buffering systems and contributes the element phosphorus, which is why this compound is often considered for applications beyond pure synthesis, such as flame-retardant formulations for suitable base materials.
In Indonesian laboratories, a stable and easily handled guanidine source is particularly welcome, since the warm and humid working environment is unkind to hygroscopic and strongly basic reagents. Working as a crystalline salt allows university synthesis groups, research institutes, and industrial R&D units to weigh the material out in ordinary bench conditions, return the remainder to storage, and draw on the same container across a series of experiments without noticeable deterioration between uses.
Laboratory Applications
Guanidino group installation: the compound delivers the guanidino fragment into a target framework, which is the core function expected of a non-heterocyclic building block in synthesis planning.
Safer substitute for free guanidine: laboratories that would otherwise handle the aggressive free base can work with the far milder phosphate salt under ordinary bench conditions.
Multi-step synthesis campaigns: because the salt tolerates long storage without loss of quality, the same container supports repeated weighings across an extended reaction sequence.
Flame-retardant formulation studies: the phosphorus contributed by the phosphate anion is the reason this compound is frequently examined in fire-resistant formulation work on suitable base materials.
Buffering-related preparations: the phosphate anion participates in buffering systems, so the material is useful where a guanidine source and a buffering counter-ion are wanted together.
Specifications
Brand: TCI, catalogue code G0165
CAS Number: 5423-23-4
Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Physical form: white crystalline solid
Pack sizes: available in the packaging options shown on this product listing
Storage: keep in a tightly closed container, protected from moisture
Handling and Storage
Store the material in its original tightly closed container in a cool, dry place away from direct sunlight and sources of heat. Glass or chemically compatible plastic containers with a well-sealing cap are suitable; make sure the lid is properly reseated after every weighing so that ambient humidity does not reach the solid. Handle the powder in a well-ventilated area or a fume hood to avoid raising dust, and wear a laboratory coat, safety glasses, and gloves as a matter of routine. Use a clean, dry spatula for each transfer to prevent cross-contamination, keep the container clearly labelled, and consult the supplier safety data sheet before first use and before disposal of any residue.
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