Gemcitabine TCI G0544

Name: TCI G0544 95058-81-4 Gemcitabine
Brand: TCI
SKU: TCI2510G054432189
Price: 1830150.0 IDR
Availability: InStock

Rp 1.830.150,00

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Berat 1g

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Description

Gemcitabine is a synthetic nucleoside widely used in biomedical research, particularly in pharmacology and biochemistry. As a key compound in the study of antitumor mechanisms, it plays a vital role in understanding how cancer cells respond to therapeutic agents. Its unique molecular structure allows it to interact with DNA, thereby inhibiting RNA synthesis and disrupting cell proliferation. This makes it an essential tool for researchers exploring the molecular basis of cancer and developing targeted therapies. In laboratory settings, gemcitabine is frequently employed to test drug efficacy, assess toxicity, and create in vitro cancer models.

Gemcitabine is valued for its chemical stability and solubility in organic solvents such as ethanol and acetone. These properties make it easy to handle and incorporate into various experimental protocols. Its ability to bind to DNA and interfere with nucleic acid synthesis positions it as a preferred choice for studies involving DNA damage, repair mechanisms, and gene expression. Additionally, gemcitabine is available in both solid and solution forms, offering flexibility in experimental design and application. This versatility enhances its utility across different research areas, from basic science to applied pharmaceutical development.

In Indonesian laboratories, gemcitabine is commonly used in cancer-related research, including drug screening, toxicity testing, and cell culture experiments. Its relevance extends to academic and industrial research institutions focused on oncology and molecular biology. Researchers rely on gemcitabine to investigate the mechanisms of cancer progression and evaluate potential therapeutic interventions. Its consistent performance and reliability make it a trusted component in the toolkit of Indonesian scientists working in life sciences and biomedical fields.

Laboratory Applications

Cancer drug development studies benefit from gemcitabine's ability to inhibit DNA synthesis, making it ideal for evaluating antitumor compounds.
Toxicity testing in vitro uses gemcitabine to assess cellular response to chemotherapeutic agents and identify potential side effects.
Cell culture experiments often incorporate gemcitabine to study how cancer cells respond to DNA-targeting drugs and their metabolic pathways.
DNA damage and repair research utilizes gemcitabine to investigate how nucleoside analogs affect genetic material and cellular function.
In vitro tumor model creation relies on gemcitabine to simulate the effects of chemotherapy on cancerous cells and monitor treatment outcomes.

Specifications

Brand: TCI
CAS number: 95058-81-4
Category: Life Science > Biochemicals and Reagents > Nucleosides, Nucleotides, Oligonucleotides
Pack sizes: Available in various quantities as per standard laboratory supply practices
Physical form: Solid (as per standard product specifications)
Storage note: Store in a cool, dry place away from light and moisture

Handling and Storage

Gemcitabine should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to air and contaminants. When handling, researchers should wear appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety. Gemcitabine is generally stable under standard laboratory conditions but should be kept in a secure location to prevent accidental spills or contamination. Proper labeling of containers is essential for safe handling and to avoid mix-ups with other reagents. Adherence to standard laboratory safety protocols ensures the safe and effective use of gemcitabine in research settings.