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TCI

CAS 2353-33-5

5-Aza-2'-deoxycytidine TCI A2232

5-Aza-2'-deoxycytidine TCI A2232

Chemical Identity

CAS No.
2353-33-5
PubChem
CID 24848394·SID 160871263
Formula
C8H12N4O4
Molecular weight
228.21 g/mol
Purity
>98.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
4-amino-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
SMILES
C1[C@@H](O[C@@H](C1O)CO)N2C=NC(=NC2=O)N
InChIKey
XAUDJQYHKZQPEU-YSLANXFLSA-N
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5-Aza-2'-deoxycytidine is a chemical compound widely used in biochemical and molecular biology research. It functions as a nucleotide analog, playing a crucial role in DNA modification, particularly in the process of DNA demethylation. This compound is essential for studying epigenetic mechanisms and gene regulation, making it a valuable tool in modern laboratory settings. Its ability to inhibit methyltransferase activity allows researchers to explore how DNA methylation affects gene expression and cellular differentiation.

The compound's chemical properties make it a preferred choice for laboratory applications. It has a stable structure under controlled conditions, enabling consistent results in experiments. Its similarity to natural nucleotides allows it to integrate easily into DNA during synthesis, making it ideal for targeted DNA modifications. The solid form and ease of dissolving in solution further enhance its practicality for use in various experimental protocols.

In Indonesian laboratories, 5-Aza-2'-deoxycytidine is commonly used in epigenetic studies, cell biology, and cancer research. Researchers rely on this compound to investigate the role of DNA methylation in disease progression and to develop therapeutic strategies. Its availability and ease of handling make it a practical choice for both academic and industrial research settings in Indonesia.

  • Epigenetic Research: This compound is used to study DNA demethylation and its impact on gene expression, offering insights into cellular differentiation and disease mechanisms.
  • Cancer Research: It helps in understanding how DNA methylation contributes to oncogenesis and in developing targeted therapies for malignant conditions.
  • Gene Regulation Studies: Its ability to inhibit methyltransferase makes it ideal for investigating the epigenetic control of gene activity in various biological systems.
  • Molecular Biology Experiments: It is frequently used in DNA modification protocols, enabling precise manipulation of genetic material for functional studies.
  • Cellular Differentiation Studies: Researchers use it to explore how methylation patterns influence cell fate and developmental processes in different cell types.

Brand TCI
CAS number 2353-33-5
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Nucleic Acid Chemistry
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid
Storage Store in a cool, dry place away from moisture and direct light

5-Aza-2'-deoxycytidine should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is sensitive to moisture and should be kept in airtight containers to avoid exposure to air and humidity. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. It is recommended to store it in a desiccator or a sealed container to minimize environmental exposure. Proper labeling and storage conditions are essential to ensure the compound remains effective for research applications. Regular monitoring of storage conditions will help maintain its integrity and usability in experimental settings.

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