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CAS 942-92-7

Hexanophenone TCI H0116

Hexanophenone TCI H0116
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TCI H0116 Hexanophenone is an aromatic-aliphatic ketone that joins a phenyl ring to a hexanoyl chain, which is why it is also commonly written as 1-phenyl-1-hexanone. This hybrid structure places the compound between two worlds: the aromatic character contributed by the benzene ring and the lipophilic character contributed by the long alkyl chain. In the laboratory, it is used as a starting material for the synthesis of aromatic derivatives, as a model compound in photochemical studies of aryl alkyl ketones, and as a reference standard in chromatographic work that calls for an analyte with reasonably long retention on reversed-phase columns.

The main property that leads researchers to select Hexanophenone is the carbonyl group conjugated with the aromatic ring. This conjugation lowers carbonyl reactivity compared with a purely aliphatic ketone, while at the same time producing a characteristic ultraviolet absorption and interesting photochemical behaviour, including the Norrish-type reactions that are frequently examined in mechanistic studies. The long hexyl chain adds lipophilicity, so the behaviour of the compound is easy to predict in non-polar solvent systems and on chromatographic columns. Reagent-grade purity keeps the resulting spectroscopic data clean and straightforward to interpret.

In Indonesian laboratories, Hexanophenone is typically found in university organic synthesis groups, in instrumental analysis laboratories that develop and verify reversed-phase methods, and in research units studying the photochemistry of carbonyl compounds. It is normally ordered in modest quantities suited to bench-scale synthesis and method development work, where a well-characterised aryl alkyl ketone is needed as a building block, a model substrate, or a retention reference rather than as a bulk process chemical.

  • Aromatic derivative synthesis — the conjugated carbonyl serves as a reliable handle for building larger aromatic structures, giving predictable reactivity while the phenyl ring remains intact throughout the transformation.
  • Photochemical mechanism studies — as a classic aryl alkyl ketone it undergoes Norrish-type reactions, making it a well-behaved model substrate for teaching and investigating excited-state carbonyl pathways.
  • Reversed-phase chromatography reference standard — the long hexyl chain gives sufficiently long retention on C18 columns, which is useful when checking column performance or calibrating retention behaviour across a method.
  • Ultraviolet spectroscopy reference work — conjugation between the carbonyl and the benzene ring produces a characteristic absorption, so the compound is convenient for verifying detector response and wavelength settings.
  • Non-polar solvent system studies — the pronounced lipophilicity from the alkyl chain makes solubility and partitioning behaviour easy to anticipate when developing extraction or formulation experiments at bench scale.

Brand TCI
CAS number 942-92-7
Molecular formula
Purity
Category Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes available in standard TCI catalogue pack sizes; please confirm the currently listed option when ordering
Physical form
Storage keep in a cool, dry place in a tightly closed container, protected from light
  • Chemical name: Hexanophenone (also known as 1-phenyl-1-hexanone)
  • Grade: reagent grade, suitable for synthesis and analytical reference use

Store Hexanophenone in a cool, dry, well-ventilated area inside a tightly closed container, keeping it away from direct sunlight and from sources of heat or ignition. Amber glass bottles with chemically resistant caps are appropriate, since protection from light supports the stability of the photochemically active carbonyl group. Handle the material inside a fume hood and wear standard laboratory protective equipment, including safety goggles, a laboratory coat, and chemically resistant gloves. Avoid contact with skin and eyes and avoid breathing vapours. Keep the compound separate from strong oxidising agents and strong bases. Always consult the manufacturer's safety data sheet before use, and dispose of residues through the laboratory's designated chemical waste route.