TCI
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Description
TCI H0203 Benzenesulfohydroxamic Acid is an organic reagent that combines a benzenesulfonyl group with a hydroxylamine group, forming the distinctive sulfonohydroxamate framework with a nitrogen-oxygen bond within it. Compounds of this class are used in organic synthesis laboratories as specialty reagents rather than as bulk materials, because their role is typically limited to a specific transformation step within a synthetic route. Their presence in a laboratory materials collection is generally intended for research work that requires a reagent with specific reactivity and that cannot be substituted by simpler, more common reagents.
The principal characteristic that governs how this material is used is the presence of a relatively weak nitrogen-oxygen bond. A bond of this kind allows the molecule to release a reactive fragment readily under certain conditions, and it is precisely this property that is exploited in synthetic reactions. However, the same property also means the compound is more sensitive to heat than ordinary aromatic reagents, so its handling demands discipline regarding storage temperature and caution during heating. The aromatic sulfonyl group itself contributes structural stability to the molecule.
In Indonesian laboratories, a reagent of this type is normally found in university research groups and institutional synthesis facilities rather than in routine testing laboratories. It is typically ordered in small quantities for a defined project, used within a specific step of a synthetic sequence, and stored under controlled conditions between experiments. Because it is a specialty reagent, purchasing is usually planned around actual experimental need rather than held as general stock.
Laboratory Applications
- Organic synthesis research: serves as a specialty reagent for defined transformation steps within a synthetic route where simpler common reagents cannot deliver the required reactivity.
- Building block chemistry: functions as a non-heterocyclic building block, allowing researchers to introduce the sulfonohydroxamate framework into target structures during multi-step preparative work.
- Nitrogen-oxygen bond chemistry: the relatively weak nitrogen-oxygen bond enables controlled release of a reactive fragment under defined conditions, a property deliberately exploited in synthetic reaction design.
- Academic method development: suits university research groups developing or reproducing synthetic procedures that require a reagent with specific, well-defined reactivity rather than general-purpose chemistry.
- Small-scale preparative chemistry: appropriate for reactions run at research scale, where the reagent is consumed in a single defined step rather than used as a bulk starting material.
Specifications
- Brand: TCI
- CAS Number: 599-71-3
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Pack sizes: available in research-scale quantities; please refer to the packaging options listed on this page
- Physical form: solid organic reagent
- Storage note: requires controlled storage temperature due to heat sensitivity
Handling and Storage
Store this reagent under controlled temperature conditions, as the nitrogen-oxygen bond makes it more sensitive to heat than ordinary aromatic reagents. Keep the material in its original tightly closed container, protected from heat sources and direct sunlight, and return it to controlled storage promptly after each use. Handle in a well-ventilated area or fume hood using standard personal protective equipment, including gloves, safety glasses, and a laboratory coat. Exercise particular caution during any heating step, and consult the manufacturer's safety data sheet before first use.
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