trans-10-Hydroxy-2-decenoic Acid TCI H1337

Chemical Identity

CAS No.: 14113-05-4
PubChem: CID 5312738·SID 253661923
Formula: C10H18O3
Molecular weight: 186.25 g/mol
Purity: >97.0%(GC)(T)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (E)-10-hydroxydec-2-enoic acid
SMILES: C(CCC/C=C/C(=O)O)CCCO
InChIKey: QHBZHVUGQROELI-SOFGYWHQSA-N

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TCI H1337, with CAS number 14113-05-4, is trans-10-Hydroxy-2-decenoic Acid, an unsaturated fatty acid built on a ten-carbon chain that carries a hydroxy group at the terminal position. The compound is widely recognised as a characteristic component of royal jelly, the honeybee secretion that serves as feed for the queen bee, and it is frequently cited as the principal quality marker for that product. In the laboratory the material plays a dual role: it serves as an analytical reference standard for determining content in royal jelly products, and it acts as a test compound in biological activity research examining antimicrobial and anti-inflammatory properties as well as effects on cell differentiation.

The property that makes this compound a preferred choice is its amphiphilic structure, which combines a hydrocarbon chain with a carboxylate group at one end and a primary hydroxy group at the other. The double bond at the two position in the trans configuration provides a conjugated unsaturated carbonyl system that increases reactivity toward nucleophiles while also being closely associated with the biological activities that have been reported for the molecule. Because the two functional groups sit far apart on the chain, selective modification at each end is possible, for example esterification of the carboxylate or oxidation chemistry at the hydroxy terminus.

In Indonesian laboratories this material is typically handled in analytical and research settings where royal jelly and apiculture products are evaluated, including quality control work on bee-derived preparations and academic research programmes. It is also used in synthetic chemistry groups that require a defined non-heterocyclic building block with two addressable functional ends. Typical users include university research laboratories, government testing institutions, and private analytical service providers working on natural product characterisation.

Related TCI products

Royal jelly quality assessment, where the compound serves as the recognised principal marker substance whose measured content indicates the grade of the finished product.
Analytical reference standard preparation, since a defined single compound is required to calibrate instrument response before content determination in royal jelly sample matrices.
Antimicrobial activity screening, in which the amphiphilic fatty acid structure is evaluated as a test compound against microbial targets under controlled research conditions.
Anti-inflammatory research studies, where the molecule is applied as a defined test substance to investigate the biological responses reported for this royal jelly constituent.
Synthetic building block applications, because the widely separated carboxylate and primary hydroxy groups permit selective esterification or oxidation at either end of the chain.

Brand	TCI (Tokyo Chemical Industry)
CAS number	14113-05-4
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	refer to the manufacturer packaging and label for the pack configurations and storage temperature applicable to this item
Physical form	—
Storage	—

Product code: H1337
Chemical class: unsaturated hydroxy fatty acid, non-heterocyclic building block

Store this material in its original tightly closed container, following the storage temperature stated on the manufacturer label. Keep the container in a cool, dry, well-ventilated chemical storage area away from direct sunlight, heat sources, and strong oxidising agents, since the conjugated unsaturated system can be sensitive to oxidative conditions. Glass containers with chemically resistant closures are suitable for subdividing working portions. Handle the compound in a fume hood using safety glasses, laboratory gloves, and a laboratory coat. Avoid contact with skin and eyes and avoid inhalation of dust. Close the container promptly after weighing to limit moisture uptake and atmospheric exposure, and consult the manufacturer safety data sheet before first use and before disposal.

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