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TCI

CAS 55321-99-8

3-Hydroxypyrazine-2-carboxamide TCI H1485

3-Hydroxypyrazine-2-carboxamide TCI H1485

Chemical Identity

CAS No.
55321-99-8
PubChem
CID 294642·SID 253660706
Formula
C5H5N3O2
Molecular weight
139.11 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-oxo-1H-pyrazine-3-carboxamide
SMILES
C1=CN=C(C(=O)N1)C(=O)N
InChIKey
SZPBAPFUXAADQV-UHFFFAOYSA-N
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3-Hydroxypyrazine-2-carboxamide is a versatile organic compound widely used in laboratory settings for its role in synthetic chemistry. As a heterocyclic building block, it serves as a key intermediate in the synthesis of complex organic molecules. Its structural characteristics make it an essential tool for researchers aiming to develop new compounds with specific functional properties. This compound is particularly valuable in the creation of pharmaceuticals, industrial chemicals, and functional materials due to its reactivity and compatibility with various synthetic pathways.

The compound’s unique properties, including its solubility in organic solvents and its ability to participate in substitution, coupling, and ring-forming reactions, make it a preferred choice for chemists. Its stable chemical nature under controlled conditions ensures reliable performance during experiments, reducing the risk of unwanted side reactions. These characteristics contribute to its widespread use in both academic and industrial research environments.

In Indonesian laboratories, 3-Hydroxypyrazine-2-carboxamide is commonly utilized in pure and applied chemical research. It is a staple in university laboratories and research institutions, where it is employed to explore the synthesis of heterocyclic compounds. The availability of this compound through AMI Scientific supports ongoing scientific investigations and educational activities in the field of organic chemistry.

Advantages (TCI brochure)

  • Viral RNA polymerase inhibitor
  • Structural analog of favipiravir

  • Organic synthesis research benefits from this compound due to its reactivity in forming heterocyclic structures and its compatibility with various synthetic methods.
  • Pharmaceutical development utilizes 3-Hydroxypyrazine-2-carboxamide for the creation of new drug molecules with targeted biological activities.
  • Industrial chemical production relies on this compound for the synthesis of functional materials and specialty chemicals with specific properties.
  • Academic research in chemical sciences employs it to study reaction mechanisms and the behavior of heterocyclic compounds under different conditions.
  • Analytical chemistry applications use it as a reference standard for the identification and quantification of similar compounds in complex mixtures.

From the TCI brochure

  • Research on antiviral activity against RNA viruses

Brand TCI
CAS number 55321-99-8
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes Available in standard laboratory quantities
Physical form Solid powder
Storage Store in a cool, dry place away from direct sunlight

3-Hydroxypyrazine-2-carboxamide should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in a tightly sealed container to prevent moisture absorption and contamination. Due to its organic nature, it is best stored in glass or high-density polyethylene containers to ensure compatibility and prevent degradation. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment when necessary. The compound is generally stable under normal laboratory conditions, making it suitable for routine use in chemical synthesis and research applications. Proper storage and handling practices help ensure the compound remains effective and safe for use in various experimental settings.

References cited in the TCI brochure

  1. Yousuke Furuta. T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections Antiviral Research, 2009. doi:10.1016/j.antiviral.2009.02.198
  2. Sangita Venkataraman. RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution Viruses, 2018. doi:10.3390/v10020076