TCI M0382 2-Methylpentane, commonly known as isohexane, is a branched saturated aliphatic hydrocarbon with the molecular formula C6H14. The compound is a clear, highly volatile liquid that belongs both to the non-heterocyclic building block group and to the family of pure hydrocarbon solvents. In the laboratory, its role is most often that of a nonpolar solvent and an inert reaction medium, as well as a reference compound in gas chromatography analysis. Because its carbon chain is branched yet fully saturated, this material takes almost no part in most organic transformations, making it safe for dissolving sensitive reagents without interfering with the course of a reaction.
The properties that make isohexane a preferred choice are its very low polarity, its low boiling point, and its chemically inert nature. Low polarity makes it excellent at dissolving fats, oils, hydrocarbons, and other nonpolar organic compounds, while the low boiling point allows the solvent to be evaporated quickly with a rotary evaporator or a stream of nitrogen without damaging heat-sensitive analytes. Compared with n-hexane, the branched structure gives a slightly different dissolving profile and chromatographic retention time, which is often useful when a method needs a hydrocarbon solvent with marginally different selectivity.
In Indonesian laboratories, 2-Methylpentane is typically used in organic synthesis work, in sample preparation for instrumental analysis, and in routine extraction of nonpolar materials. Academic research laboratories, quality control units, and analytical service laboratories draw on it whenever a clean hydrocarbon solvent is required that leaves no residue after evaporation. Its status as a non-heterocyclic building block also places it in the reagent inventory of groups working on hydrocarbon chemistry and solvent method development.
- Nonpolar solvent for organic synthesis, where its inert saturated structure dissolves reagents and substrates without joining the reaction or generating unwanted side products.
- Inert reaction medium for sensitive chemistry, since the branched saturated hydrocarbon backbone resists most transformations and keeps the chemical environment of the reaction genuinely neutral.
- Reference compound in gas chromatography, where its defined branched structure gives a reproducible retention behaviour useful for checking column performance and identifying peaks.
- Extraction of fats, oils, and nonpolar organic compounds, because very low polarity makes it strongly selective for lipophilic material while leaving polar matrix components behind.
- Sample preparation for heat-sensitive analytes, as the low boiling point permits rapid removal under rotary evaporation or nitrogen flow without thermally degrading the target compound.
| Brand | TCI (Tokyo Chemical Industry) |
|---|---|
| CAS number | 107-83-5 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | available in standard TCI packaging; please confirm the currently listed pack options when ordering |
| Physical form | clear, highly volatile liquid |
| Storage | keep in a cool, well-ventilated place away from heat and ignition sources |
- Catalogue number: M0382
2-Methylpentane is a highly volatile hydrocarbon liquid and should be stored in a cool, well-ventilated area, away from heat, sparks, open flames, and other ignition sources. Keep it in tightly closed original containers or in solvent bottles made of compatible material, and store it separately from strong oxidising agents. Handle the solvent inside a fume hood to limit vapour inhalation and vapour accumulation in the work area, and wear safety goggles, chemical-resistant gloves, and a laboratory coat. Ground containers where appropriate when transferring larger volumes, and keep the container closed when not in active use to reduce evaporation losses. Dispose of residues and solvent-contaminated waste as flammable organic waste according to the laboratory's standard waste procedures.
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