TCI M2188 Methyl-PEG12-NHS Ester is a chemical compound widely used in biochemical and biomedical applications within laboratory settings. This reagent plays a crucial role in PEGylation, a process that modifies molecules to enhance their functional properties and stability. It is commonly employed in conjugation reactions to link biological molecules such as proteins, peptides, and nucleic acids. Its utility extends across various research fields, including drug development and molecular biology, where it supports the creation of more stable and biocompatible molecular structures.
The compound's unique structure, featuring a polyethylene glycol (PEG) chain attached to an NHS ester group, makes it a preferred choice for covalent bonding with amino groups on target molecules. This property ensures high reactivity and specificity, which are essential for successful conjugation reactions. Additionally, its stability under laboratory conditions ensures consistent performance and reliability in experimental protocols. These characteristics make TCI M2188 a versatile and effective tool for researchers seeking to modify biomolecules with precision.
In Indonesian laboratories, TCI M2188 is a valuable resource for biomedical, pharmacological, and biotechnological research. It is frequently used in academic and research institutions to develop new therapeutic agents and diagnostic tools. Its ability to improve solubility, reduce toxicity, and extend molecular retention in the body makes it an essential component in advanced laboratory workflows. Its widespread application highlights its importance in supporting cutting-edge research in Indonesia.
- Biomedical Research: TCI M2188 is ideal for conjugating proteins and peptides to enhance their stability and solubility in biological systems.
- Drug Development: It supports the modification of therapeutic molecules to improve their pharmacokinetic properties and reduce immunogenicity.
- Molecular Biology: The compound is used to attach nucleic acids to solid supports, enabling efficient purification and analysis techniques.
- Diagnostic Testing: It facilitates the creation of conjugated probes for enhanced detection and specificity in diagnostic assays.
- Biotransformation Studies: TCI M2188 enables the study of molecular interactions and modifications, providing insights into biological processes.
| Brand | TCI |
|---|---|
| CAS number | — |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > PEGylation |
| Pack sizes | Available in various quantities as per standard laboratory supply |
| Physical form | Solid or liquid, depending on formulation |
| Storage | Store at controlled room temperature, away from moisture and light |
TCI M2188 should be stored in a cool, dry place, away from direct sunlight and sources of heat. It is recommended to keep the compound in a tightly sealed container to prevent exposure to moisture, which can affect its stability. In laboratory settings, it is important to handle the material with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety. The compound should be used in a well-ventilated area to minimize inhalation risks. Proper labeling of containers is essential to avoid contamination and ensure safe handling. Regular monitoring of storage conditions helps maintain the integrity and effectiveness of the reagent for long-term use.
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