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TCI

CAS 108963-96-8

Methyl N-(tert-Butoxycarbonyl)-L-pyroglutamate TCI M2803

Methyl N-(tert-Butoxycarbonyl)-L-pyroglutamate TCI M2803

Chemical Identity

CAS No.
108963-96-8
PubChem
CID 10868485·SID 354334823
Formula
C11H17NO5
Molecular weight
243.26 g/mol
Purity
>98.0%(GC)
Reference databases
ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
1-O-tert-butyl 2-O-methyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate
SMILES
CC(C)(C)OC(=O)N1[C@@H](CCC1=O)C(=O)OC
InChIKey
FNTAOUUEQHKLIU-ZETCQYMHSA-N
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Methyl N-(tert-Butoxycarbonyl)-L-pyroglutamate is a chemical compound widely used in peptide chemistry and biochemical research. This compound plays a crucial role in the synthesis of peptides, where it serves as a protected amino acid derivative. Its structure allows for controlled chemical reactions during the synthesis process, ensuring the formation of stable and accurate peptide bonds. In laboratory settings, it is essential for researchers working on protein engineering, drug development, and molecular biology applications.

The compound’s unique properties, particularly its tert-butoxycarbonyl group, make it a preferred choice for chemists and biochemists. This functional group provides stability during synthesis, reducing unwanted side reactions and improving the efficiency of peptide construction. Its chemical stability under specific conditions also enhances its usability in long-term research projects. These characteristics make it a reliable and versatile reagent for advanced laboratory work.

In Indonesian laboratories, Methyl N-(tert-Butoxycarbonyl)-L-pyroglutamate is commonly used in biochemical, pharmacological, and food science research. It is a key component in studies involving peptide synthesis, amino acid modification, and the investigation of biological activities of various compounds. Its availability and reliability have made it a staple in academic and industrial research settings across Indonesia.

TCI brochures (PDF)

  • Peptide Synthesis: This compound is ideal for peptide synthesis due to its protected amino acid structure, which allows for controlled and efficient bond formation.
  • Amino Acid Modification: It is used to modify amino acids in biochemical experiments, enabling the study of their functional roles in proteins and enzymes.
  • Biological Activity Studies: Researchers use it to investigate the biological activity of compounds, particularly in drug discovery and molecular biology.
  • Protein Engineering: Its role in forming stable peptide bonds makes it valuable in protein engineering and structural biology research.
  • Food Science Research: It is applied in food science to study the chemical composition and functional properties of peptides in food products.

Brand TCI
CAS number 108963-96-8
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid powder
Storage Store in a cool, dry place away from moisture and direct sunlight

This compound should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to use airtight containers to protect it from moisture and contaminants. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Avoid exposure to heat and direct sunlight, as these conditions may affect its integrity. Proper labeling of containers is essential for safe handling and to prevent cross-contamination. Always follow standard laboratory safety protocols when working with this compound.

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