Mangiferin TCI M2886

Chemical Identity

CAS No.: 4773-96-0
PubChem: CID 5281647·SID 468592226
Formula: C19H18O11
Molecular weight: 422.3 g/mol
Purity: >97.0%(HPLC)(T)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one
SMILES: C1=C2C(=CC(=C1O)O)OC3=C(C2=O)C(=C(C(=C3)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O
InChIKey: AEDDIBAIWPIIBD-ZJKJAXBQSA-N

Rp 2.702.700,00

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Mangiferin from TCI is a natural product compound from the xanthone class, carrying a glucose unit attached through a C-glycosidic bond. It is best known as a compound that can be isolated from parts of the mango plant (Mangifera indica), such as the leaves and stem bark, as well as from a number of other plants. TCI lists Mangiferin in its Glycoscience group. In the laboratory, it serves as a reference standard in phytochemical analysis and as a test compound in research on the biological activity of natural products, including antioxidant and pharmacological studies.

What makes Mangiferin structurally interesting is its C-glycosidic bond, which resists acid and enzymatic hydrolysis far better than the more common O-glycosides. Because of this, the sugar portion of the molecule does not readily split off during sample preparation or within biological systems. The xanthone core carries several phenolic hydroxyl groups, which allow it to scavenge free radicals. This property has driven extensive research into its potential as an antioxidant, anti-inflammatory and cell-protective agent. Research that needs reproducible results depends on a pure compound with a clearly established identity, which is why a well-characterized source matters.

Indonesia is one of the world's mango-producing countries and has a wide diversity of plant species, so Mangiferin is relevant to many local research programmes. University pharmacy and chemistry departments, natural product research groups and herbal medicine development laboratories can use it to identify and quantify Mangiferin in extracts of local plant material. It also supports student research projects, method development work and comparative studies of bioactive compounds from Indonesian flora.

TCI brochures (PDF)

Phytochemicals 2025-12-17 · p. 13

Related TCI products

Phytochemical reference standard: Mangiferin serves as a comparison compound for identifying and quantifying this xanthone in plant extracts, especially material derived from mango leaves and stem bark.
Antioxidant activity studies: the phenolic hydroxyl groups on its xanthone core give it free-radical scavenging ability, so it suits antioxidant assays as a test compound or positive comparison.
Pharmacological research on natural products: Mangiferin is widely studied for anti-inflammatory and cell-protective potential, so it suits laboratories screening the biological activity of plant-derived compounds.
Glycoscience and C-glycoside studies: its C-glycosidic bond resists acid and enzymatic hydrolysis, which makes it a useful model compound for comparing glycoside stability against common O-glycosides.
Quality control of herbal raw materials: laboratories that develop herbal products from Indonesian plants can use Mangiferin as a marker compound to check the identity and consistency of extracts.

Brand	TCI (product code M2886)
CAS number	4773-96-0
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Glycoscience
Pack sizes	available in the pack sizes listed in the current TCI catalog
Physical form	—
Storage	follow the conditions stated on the TCI label and Safety Data Sheet

Compound class: xanthone C-glycoside of natural origin

Keep Mangiferin in its original, tightly closed manufacturer container in a cool, dry place away from direct sunlight and moisture, under the conditions stated on the TCI label. Reseal the container straight after each use to limit exposure to air and humidity. Handle the material in a clean, well-ventilated area and wear standard laboratory protection, including gloves, safety glasses and a lab coat. Avoid creating or breathing in dust, and avoid contact with skin and eyes. Use clean, dry spatulas to prevent cross-contamination, and label any prepared solutions clearly. Read the Safety Data Sheet before use and dispose of waste in line with institutional and local regulations.

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