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TCI

CAS 145525-41-3

Mitiglinide Calcium TCI M3177

Mitiglinide Calcium TCI M3177

Chemical Identity

CAS No.
145525-41-3
PubChem
CID 5478927·SID 468592314
Formula
C38H48CaN2O6
Molecular weight
668.9 g/mol
Reference databases
ChEBI·ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
calcium bis((2S)-4-[(3aR,7aS)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]-2-benzyl-4-oxobutanoate)
SMILES
C1CC[C@H]2CN(C[C@H]2C1)C(=O)C[C@H](CC3=CC=CC=C3)C(=O)[O-].C1CC[C@H]2CN(C[C@H]2C1)C(=O)C[C@H](CC3=CC=CC=C3)C(=O)[O-].[Ca+2]
InChIKey
PMRVFZXOCRHXFE-FMEJWYFOSA-L
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Mitiglinide Calcium with CAS number 145525-41-3 is a pharmaceutical research reagent from TCI that belongs to the group of insulinotropic compounds in the glinide (meglitinide) class. In the laboratory, this material is used as a test and reference compound in pharmacological research on carbohydrate metabolism, particularly in studies of the insulin release mechanism through modulation of ATP-sensitive potassium channels in pancreatic beta cells. It is supplied specifically for experimental work and method development purposes, not for clinical use in humans, so it is placed on a controlled research reagent shelf together with other pharmaceutical reference materials that require orderly usage records.

The characteristic that makes this material a preferred choice is its form as a calcium salt, which generally gives a solid that is more practical to handle than the free acid form and is therefore easier to weigh at the milligram scale. The compound identity tied to one specific CAS number makes literature searching and cross-verification against published data straightforward, which matters when a reference compound has to be matched exactly to the substance described in a cited method. Small pack sizes of 100 mg and 500 mg are consistent with the usage pattern of pharmaceutical research reagents, which are normally consumed in limited quantities per experimental series.

In Indonesian laboratories, a reagent of this type sits on a controlled research shelf alongside other pharmaceutical reference materials whose use is logged in an orderly manner. Because it is supplied strictly for experimental and method development purposes and not for human clinical use, its handling is kept within the research setting. The small packaging suits laboratories that run a limited number of experimental series and prefer to avoid holding larger quantities of a pharmaceutical reference compound than a study requires.

  • Carbohydrate metabolism pharmacology studies, where this reagent serves as a defined test compound in investigations of how insulinotropic agents affect metabolic pathways under experimental conditions.
  • Insulin release mechanism research, in which the material is used to examine modulation of ATP-sensitive potassium channels in pancreatic beta cells as described in the published literature.
  • Reference compound work for the glinide (meglitinide) class, since a single specific CAS number allows the substance to be matched exactly against compounds described in cited methods.
  • Analytical method development, where the calcium salt form gives a solid that is practical to weigh accurately at the milligram scale during preparation of working solutions.
  • Literature cross-verification exercises, because the compound identity tied to CAS 145525-41-3 makes tracing published data and confirming substance identity a straightforward step.

Brand TCI
CAS number 145525-41-3
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use)
Pack sizes 100 mg and 500 mg
Physical form calcium salt, supplied as a solid
Storage keep on a controlled research reagent shelf with orderly usage records; for experimental use only, not for human clinical use

Store this reagent in its original closed container on a controlled research reagent shelf, kept together with other pharmaceutical reference materials whose use is recorded in an orderly manner. Keep the container tightly sealed when not in use and return it to its designated place after each weighing so that the small 100 mg or 500 mg pack is not left open longer than necessary. Weigh the solid using clean, dry spatulas and suitable tared vessels to avoid cross-contamination between reference compounds. Handle the material only within the laboratory as an experimental substance, observing standard laboratory practice for pharmaceutical research reagents, and do not use it for clinical purposes in humans.

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