3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine is a heterocyclic compound widely used in chemical research as a building block for the synthesis of complex molecules. Its unique structure makes it a valuable tool in organic chemistry, enabling the development of new compounds with specific functional groups. In the laboratory, this compound plays a crucial role in the design and synthesis of pharmaceuticals, agrochemicals, and industrial chemicals. Its versatility allows chemists to modify its structure to create compounds with desired biological or chemical properties.
The compound is known for its high reactivity due to its heterocyclic framework, which facilitates various chemical reactions such as substitution and condensation. This reactivity, combined with its chemical stability under controlled conditions, makes it a preferred choice for synthetic chemists. However, it is sensitive to moisture and air exposure, requiring careful handling and storage. These properties make it suitable for applications where precise chemical transformations are necessary.
In Indonesian laboratories, 3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine is commonly used in pharmacological and organic synthesis research. It is a key component in the development of new drugs and chemical compounds. Many research institutions and universities in Indonesia rely on this compound for advancing their studies in chemistry and related fields. Its availability and chemical properties support ongoing scientific innovation in the region.
TCI brochures (PDF)
- Building Blocks for Medicinal Chemistry 2025-05-12 · p. 2
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- Organic synthesis research benefits from this compound due to its reactivity and structural versatility, enabling the creation of complex molecules with tailored properties.
- Pharmaceutical development utilizes this building block to design new drug candidates with specific biological activities and molecular structures.
- Agrochemical research employs this compound in the synthesis of pesticides and herbicides, leveraging its heterocyclic framework for enhanced chemical functionality.
- Industrial chemical production incorporates this material for the development of specialty chemicals requiring precise molecular design.
- Academic research in chemistry and pharmacology uses this compound to explore new synthetic pathways and molecular interactions in laboratory settings.
From the TCI brochure
- Inhibitor of V600E mutation of B-Raf kinase (SAR example, ref. 3)
| Brand | TCI |
|---|---|
| CAS number | 1186608-73-0 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Heterocyclic Building Blocks |
| Pack sizes | Available in various quantities as per standard chemical supply practices |
| Physical form | Solid, typically in powder or crystalline form |
| Storage | Requires storage in a dry, cool, and dark environment to prevent degradation |
This compound should be stored in a dry, cool, and dark environment to maintain its chemical stability and prevent degradation. It is recommended to use airtight containers to minimize exposure to moisture and air, which can affect its reactivity and purity. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. Due to its sensitivity, it should be kept away from sources of heat and direct sunlight. Proper labeling and storage conditions are essential to ensure safe handling and long-term usability in research applications.
References cited in the TCI brochure
- Steve Wenglowsky. Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors ACS Medicinal Chemistry Letters, 2011. doi:10.1021/ml200025q
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