7-Nitroindazole TCI N0827

Chemical Identity

CAS No.: 2942-42-9
PubChem: CID 1893·SID 87560340
Formula: C7H5N3O2
Molecular weight: 163.13 g/mol
Purity: >97.0%(GC)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 7-nitro-1H-indazole
SMILES: C1=CC2=C(C(=C1)[N+](=O)[O-])NN=C2
InChIKey: PQCAUHUKTBHUSA-UHFFFAOYSA-N

Rp 955.500,00

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7-Nitroindazole is a chemical compound widely used in scientific research, particularly in the fields of cell biology and neuroscience. It serves as a key reagent in laboratory settings where the study of cellular signaling pathways and neural activity is essential. This compound is especially valuable for its ability to inhibit phosphodiesterase enzymes, which play a crucial role in regulating intracellular levels of cyclic adenosine monophosphate (cAMP). By modulating these pathways, 7-Nitroindazole enables researchers to investigate how cells respond to various stimuli and how signaling transduction mechanisms operate within biological systems.

One of the main reasons 7-Nitazole is preferred in laboratories is its chemical stability and solubility in organic solvents such as ethyl acetate and acetone. These properties make it easy to handle and incorporate into a wide range of experimental protocols. Additionally, its solid form facilitates precise weighing and easy handling, making it ideal for small-scale experiments. The compound’s consistent performance and reliability in different experimental conditions further enhance its appeal among researchers working in life sciences.

In Indonesian laboratories, 7-Nitroindazole is commonly used in neuroscience, pharmacology, and biotechnology research. Local scientists utilize it to study the effects of stimulants on neurons and to develop new neurologically based drugs. Its application in these fields is supported by its effectiveness in inhibiting phosphodiesterase and its compatibility with various experimental techniques. The compound’s role in advancing scientific understanding in these areas is well recognized among Indonesian researchers.

TCI brochures (PDF)

Reactive Oxygen Species (ROS) and Oxidative Stress Research Reagents 2026-04-23 · p. 2
Reagents for Biological Research 2025-03-11 · p. 37

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Research on the inhibitory effects of phosphodiesterase on neuronal signaling pathways due to its selective action on enzyme activity.
Testing the biological activity of compounds in drug development to understand their impact on neural function and cellular responses.
Studying the modulation of cAMP levels in cells to explore the mechanisms behind cellular communication and signal transduction.
Supporting pharmacological studies aimed at developing new treatments for neurological disorders by analyzing compound interactions with neural tissues.
Facilitating experiments in biotechnology that require precise control over enzymatic reactions and cellular signaling processes.

Brand	TCI
CAS number	2942-42-9
Molecular formula	—
Purity	—
Category	Life Science > Cell Biology > Cell Signaling and Neuroscience
Pack sizes	Available in various quantities as per standard laboratory supply formats
Physical form	Solid
Storage	Store in a cool, dry place away from light and moisture

7-Nitroindazole should be stored in a cool, dry environment, away from direct sunlight and moisture to maintain its chemical stability. It is recommended to use airtight containers made of glass or high-density polyethylene to prevent contamination and degradation. Due to its organic solubility, it should be handled in a well-ventilated area to minimize exposure. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when handling the compound. Proper labeling of storage containers is essential to ensure safe access and prevent accidental use. The compound is non-hazardous under normal conditions but should be treated with care to avoid any potential risks associated with chemical handling.

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