Nocodazole TCI N1138

Chemical Identity

CAS No.: 31430-18-9
PubChem: CID 4122·SID 468592478
Formula: C14H11N3O3S
Molecular weight: 301.32 g/mol
Purity: >98.0%(HPLC)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
SMILES: COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
InChIKey: KYRVNWMVYQXFEU-UHFFFAOYSA-N

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Nocodazole is a chemical compound widely used in biomedical and pharmacological research. As a microtubule inhibitor, it plays a crucial role in preventing the formation of microtubules, which are essential components of cell division. In the laboratory, Nocodazole is essential for studying the mechanisms of cell division and its effects on various cell types. Its utility spans multiple research areas, making it a versatile tool for scientists. This compound is particularly valuable in investigations related to cellular changes, especially in cancer and genetic disorders.

Nocodazole is chemically stable and soluble in organic solvents such as ethyl acetate and acetone. These properties make it easy to handle and incorporate into a wide range of chemical and biological experiments. Its stability under certain conditions also facilitates long-term storage and use. The availability of high-quality Nocodazole ensures that researchers can rely on consistent results. This compound is a preferred choice due to its reliability and effectiveness in experimental settings.

In Indonesian laboratories, Nocodazole is extensively used in cell biology and pharmacology research. It is commonly found in studies focused on cellular processes and drug development. Its application is widespread across various research institutions, contributing to advancements in scientific understanding. The compound's role in experimental research makes it an essential component in the laboratory toolkit of Indonesian scientists.

TCI brochures (PDF)

Cell Cycle Analysis Kit without Cell Pre-Fixation 2024-01-25 · p. 1
Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 19
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 19

Related TCI products

Cell Cycle Research: Nocodazole is used to study the effects of microtubule disruption on cell division, aiding in understanding the mechanisms of mitosis and apoptosis.
Cancer Research: It helps in investigating the role of microtubules in tumor growth and the development of anti-cancer drugs by inhibiting cell proliferation.
Pharmacological Studies: Nocodazole serves as a tool to evaluate the efficacy of compounds that target microtubules, supporting drug discovery and development.
Genetic Disorder Analysis: It assists in studying cellular changes associated with genetic mutations, providing insights into disease progression and treatment options.
Toxicology Testing: Nocodazole is used to assess the impact of chemical exposure on cellular structures, contributing to safety evaluations in pharmaceutical and environmental research.

Brand	TCI
CAS number	31430-18-9
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Solid powder (as per standard product specifications)
Storage	Store in a cool, dry place away from light and moisture

Nocodazole should be stored in a cool, dry place away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. Due to its potential reactivity, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. In laboratory settings, it should be stored separately from incompatible substances to ensure safety. Regular monitoring of storage conditions is advised to maintain the integrity of the compound over time. Proper labeling of containers is essential for safe handling and to prevent accidental exposure.

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