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TCI

CAS 17673-25-5

Phorbol TCI P2732

Phorbol TCI P2732

Chemical Identity

CAS No.
17673-25-5
PubChem
CID 442070·SID 468592695
Formula
C20H28O6
Molecular weight
364.4 g/mol
Purity
>98.0%(HPLC)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(1S,2S,6R,10S,11R,13S,14R,15R)-1,6,13,14-tetrahydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyltetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dien-5-one
SMILES
C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)CO)O)C)O)O)O
InChIKey
QGVLYPPODPLXMB-UBTYZVCOSA-N
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Phorbol is a chemical compound classified under the terpenoid category, known for its complex molecular structure and significant role in various biochemical reactions. It is widely used in laboratory settings for studying cellular activation mechanisms, particularly in pharmacology and cell biology. As a key activator of protein kinase C (PKC), Phorbol plays a crucial role in signal transduction pathways within cells. Its ability to influence cellular responses to external stimuli makes it an essential tool for researchers exploring the dynamics of cellular behavior and signaling processes.

Phorbol is valued for its chemical stability under controlled conditions, despite its sensitivity to moisture and UV light exposure. Its complex molecular structure requires careful handling to ensure accurate experimental results. The compound’s biological activity necessitates precise handling to avoid unintended side effects. These properties make Phorbol a preferred choice for laboratories conducting advanced biochemical and pharmacological research, where reproducibility and reliability are paramount.

In Indonesian laboratories, Phorbol is commonly used in biomedical and pharmaceutical research. It is integral to experiments focused on cellular activation mechanisms, especially in drug development and cellular therapy studies. Researchers across various institutions rely on Phorbol to investigate the molecular pathways involved in cellular responses, contributing to advancements in both basic and applied scientific research.

TCI brochures (PDF)

  • Cellular signaling research: Phorbol is used to study the activation of protein kinase C, which is central to intracellular signaling pathways.
  • Pharmacological studies: It helps in understanding how certain compounds influence cellular responses and signal transduction mechanisms.
  • Drug development: Phorbol is employed in the exploration of molecular targets for therapeutic interventions in disease treatment.
  • Biochemical assays: Its role as a reagent enables the investigation of enzyme activity and cellular response to external stimuli.
  • Cellular therapy research: It supports experiments aimed at understanding and manipulating cellular behavior for therapeutic applications.

Brand TCI
CAS number 17673-25-5
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Terpenes
Pack sizes —
Physical form —
Storage Store in a cool, dry place away from light and moisture

Phorbol should be stored in a cool, dry environment, away from direct sunlight and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and UV light, which can degrade the compound. Due to its biological activity, proper handling is essential to avoid contamination or unintended effects during experiments. Laboratories should ensure that Phorbol is kept in a secure location, away from incompatible substances. Regular monitoring of storage conditions is advised to ensure the integrity of the material for reliable research outcomes.

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