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Description
3-Phenylbutanal is an aromatic aldehyde compound that plays an important role as a building block in organic synthesis within the laboratory. This compound, bearing the CAS number 16251-77-7, belongs to the category Chemistry > Building Blocks > Non-Heterocyclic Building Blocks, which means it is used as a starting material for constructing more complex molecules through various chemical reactions. In the laboratory, it is commonly employed as a precursor in the preparation of intermediates, active pharmaceutical ingredients, fragrance substances, and other fine chemical compounds.
The presence of an aldehyde group and a phenyl ring in its structure makes this compound reactive toward a wide range of reagents, giving it great flexibility for conversion into alcohols, carboxylic acids, amines, or other derivatives. One of the main characteristics that make 3-Phenylbutanal a preferred choice is the balance between reactivity and stability offered by the aliphatic aldehyde group attached to a chain that contains a phenyl ring. This balance allows researchers to run selective transformations under ordinary laboratory conditions while still retaining the versatility expected from a reactive aldehyde intermediate.
In Indonesian research laboratories, 3-Phenylbutanal is typically used as a starting material in multi-step synthetic routes, where it serves as a versatile scaffold for building larger molecular frameworks. It is frequently applied in the development of intermediates for pharmaceutical research, in the preparation of aroma and flavor-related compounds, and in academic teaching laboratories that demonstrate fundamental aldehyde chemistry. Its position within the Building Blocks category makes it a routine item in the reagent inventory of synthetic chemistry and materials chemistry groups across the country.
Laboratory Applications
Synthesis of organic intermediates – 3-Phenylbutanal serves as a reliable carbon scaffold for stepwise construction of more complex intermediate molecules through condensation and addition reactions.
Pharmaceutical research – Its aldehyde functionality enables coupling with amines and other nucleophiles, making it a practical precursor for building active pharmaceutical ingredient candidates.
Fragrance and flavor chemistry – The phenyl-substituted aldehyde backbone is well suited for preparing aroma-related derivatives used in the development of scent and flavor compositions.
Reduction and oxidation studies – The aldehyde group can be selectively converted to the corresponding alcohol or carboxylic acid, making this compound a useful substrate for demonstrating redox transformations.
Academic teaching laboratories – As a representative non-heterocyclic aldehyde building block, it is ideal for demonstrating fundamental reactions such as imine formation and nucleophilic addition in practical coursework.
Specifications
Brand: TCI
Product name: TCI P3261 3-Phenylbutanal
CAS number: 16251-77-7
Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Chemical class: aromatic aldehyde (non-heterocyclic building block)
Physical form: not stated in the available product data; verify the actual form upon delivery before use
Handling and Storage
Store 3-Phenylbutanal in a cool, dry, and well-ventilated area, protected from direct sunlight and away from sources of heat and ignition. Keep the container tightly closed when not in use to minimize evaporation and exposure to air, and use containers made of materials compatible with aldehydes, such as suitably lined glass or appropriate laboratory-grade vessels. Handle the compound inside a fume hood while wearing appropriate personal protective equipment, including chemical-resistant gloves and safety glasses, and avoid contact with skin, eyes, and inhalation of vapors. Keep the material away from strong oxidizing agents and acids, and follow standard laboratory practices for safe dispensing and waste disposal.
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