Quinoline-8-boronic Acid (TCI Q0086), with CAS number 86-58-8, is a chemical compound widely used in organic reactions, particularly in the synthesis of heterocyclic compounds and coupling reactions. This reagent contains varying amounts of anhydride and is known for its ability to react with aromatic and alkyl halides, making it a versatile tool in synthetic chemistry. Its unique structure, featuring a boronic acid group attached to a quinoline ring, enables it to participate in a variety of chemical transformations.
The compound's stability and reactivity make it a preferred choice in laboratory settings. Its ability to form stable intermediates and its compatibility with various reaction conditions contribute to its popularity among chemists. The presence of the boronic acid group allows for efficient coupling reactions, especially in the Suzuki reaction, which is a key method in the synthesis of complex organic molecules. This reagent is particularly valuable for its precision and reliability in organic synthesis.
In Indonesian laboratories, Quinoline-8-boronic Acid is commonly used by researchers and students for the synthesis of new compounds and the modification of existing organic molecules. Its availability in the local market supports both research and educational activities. The compound is essential for advancing chemical studies and developing new synthetic methodologies in the field of organic chemistry.
TCI brochures (PDF)
- Suzuki-Miyaura Cross Coupling Reaction 2025-12-01 · p. 14
- Boron Compounds 2025-10-07 · p. 13
Related TCI products
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- TCI T2621 160032-40-6 Thieno[3,2-b]thiophene-2-boronic Acid (contains varying amounts of Anhydride)
- TCI T1975 6165-69-1 3-Thiopheneboronic Acid (contains varying amounts of Anhydride)
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- Synthesis of Heterocyclic Compounds: Quinoline-8-boronic Acid is ideal for creating complex ring structures due to its reactive boronic acid group, which facilitates coupling reactions with aromatic halides.
- Suzuki Coupling Reactions: This reagent is crucial in Suzuki reactions, where it enables the formation of carbon-carbon bonds under mild conditions, making it essential for organic synthesis.
- Organic Compound Modification: Its ability to react with various substrates allows for the functionalization of organic molecules, supporting the development of new chemical structures.
- Research in Medicinal Chemistry: The compound is used in the synthesis of pharmaceutical intermediates, contributing to drug discovery and development efforts.
- Educational Purposes: It is widely used in academic settings to teach advanced organic chemistry techniques and reaction mechanisms to students.
| Brand | TCI |
|---|---|
| CAS number | 86-58-8 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Organometallic Reagents > Organoboron [Organometallic Reagents] |
| Pack sizes | Available in various sizes as per supplier specifications |
| Physical form | Solid or powder, depending on the batch |
| Storage | Store in a cool, dry place away from moisture and light |
Quinoline-8-boronic Acid should be stored in a cool, dry environment to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to moisture and air, which could affect its reactivity. Due to its potential reactivity with certain substances, it should be handled in a well-ventilated area, preferably with appropriate personal protective equipment. Avoid contact with strong oxidizing agents or acids to ensure safety. The compound should be kept away from heat sources and direct sunlight to prevent degradation. Proper labeling and storage conditions are essential to ensure safe and effective use in laboratory settings.
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