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TCI

CAS 220114-03-4

RuCl2[(S)-xylbinap][(S,S)-dpen] TCI R0134

RuCl2[(S)-xylbinap][(S,S)-dpen] TCI R0134

Chemical Identity

CAS No.
220114-03-4
PubChem
CID 46912346·SID 253659928
Formula
C66H64Cl2N2P2Ru
Molecular weight
1119.1 g/mol
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
[1-[2-bis(3,5-dimethylphenyl)phosphanylnaphthalen-1-yl]naphthalen-2-yl]-bis(3,5-dimethylphenyl)phosphane;(1S,2S)-1,2-diphenylethane-1,2-diamine;ruthenium(2+);dichloride
SMILES
CC1=CC(=CC(=C1)P(C2=C(C3=CC=CC=C3C=C2)C4=C(C=CC5=CC=CC=C54)P(C6=CC(=CC(=C6)C)C)C7=CC(=CC(=C7)C)C)C8=CC(=CC(=C8)C)C)C.C1=CC=C(C=C1)[C@@H]([C@H](C2=CC=CC=C2)N)N.[Cl-].[Cl-].[Ru+2]
InChIKey
HYMSONXJNGZZBM-LISIALKWSA-L
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TCI R0134 220114-03-4 RuCl2[(S)-xylbinap][(S,S)-dpen] is a complex metal-based compound used in asymmetric synthesis to produce chiral products with specific structural configurations. This material plays a crucial role in laboratories where precise control over stereochemistry is essential. It is designed to facilitate efficient and selective chemical reactions, making it a valuable tool for researchers in various scientific disciplines. Its application is particularly relevant in the development of compounds with biological activity, where stereochemistry significantly influences the final product's properties.

The compound is preferred due to its high catalytic efficiency and ability to maintain consistent results across multiple reactions. Its chiral structure enables the formation of enantiomerically pure compounds, which is critical in pharmaceutical and organic chemistry. The stability of the compound under various reaction conditions further enhances its reliability in laboratory settings. Additionally, its compatibility with a wide range of solvents and reaction conditions makes it a versatile choice for synthetic chemists.

In Indonesian laboratories, this material is widely used in research related to pharmacology, organic chemistry, and industrial chemical development. It supports the creation of new compounds with potential medical or industrial applications. Its role in advancing scientific research is significant, especially in institutions focused on innovation and discovery. The compound’s effectiveness in asymmetric synthesis makes it an essential component in modern chemical research.

  • Asymmetric synthesis is a key application where this compound enables the selective formation of chiral products, crucial for pharmaceutical development.
  • Organic chemistry research benefits from its catalytic properties, allowing for the synthesis of complex molecules with controlled stereochemistry.
  • Pharmaceutical research utilizes this material to develop drugs with high enantiomeric purity, enhancing their therapeutic efficacy.
  • Industrial chemical development relies on its stability and efficiency to produce compounds with specific structural and functional properties.
  • Academic institutions use it in teaching and research to explore advanced synthetic methods and chiral chemistry concepts.

Brand TCI
CAS number 220114-03-4
Molecular formula —
Purity —
Category Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes —
Physical form —
Storage Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its stability and effectiveness. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its performance. Laboratory personnel should handle the material with care, using appropriate personal protective equipment such as gloves and safety goggles to minimize exposure. Due to its chemical nature, it should be kept away from incompatible substances to avoid any potential reactions. Proper labeling and storage conditions are essential to ensure safe handling and long-term usability in research settings.

References cited in the TCI brochure

  1. Takeshi Ohkuma. Asymmetric Hydrogenation of Alkenyl, Cyclopropyl, and Aryl Ketones. RuCl2(xylbinap)(1,2-diamine) as a Precatalyst Exhibiting a Wide Scope Journal of the American Chemical Society, 1998. doi:10.1021/ja983257u
  2. Takaji Matsumoto. Diastereoselective synthesis of a key intermediate for the preparation of tricyclic β-lactam antibiotics Tetrahedron Letters, 1999. doi:10.1016/s0040-4039(99)00929-6