[RuCl(p-cymene)((R)-segphos(regR))]Cl TCI R0154

Chemical Identity

CAS No.: 944451-28-9
PubChem: CID 51001217·SID 253662110
Formula: C48H42Cl2O4P2Ru
Molecular weight: 916.8 g/mol

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [4-(5-diphenylphosphanyl-1,3-benzodioxol-4-yl)-1,3-benzodioxol-5-yl]-diphenylphosphane;1-methyl-4-propan-2-ylbenzene;ruthenium(2+);dichloride
SMILES: CC1=CC=C(C=C1)C(C)C.C1OC2=C(O1)C(=C(C=C2)P(C3=CC=CC=C3)C4=CC=CC=C4)C5=C(C=CC6=C5OCO6)P(C7=CC=CC=C7)C8=CC=CC=C8.[Cl-].[Cl-].[Ru+2]
InChIKey: HZLSGDCLBWZKRB-UHFFFAOYSA-L

Rp 1.298.850,00

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Berat 200mg 1g

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TCI R0154, with the CAS number 944451-28-9, is a chiral catalyst used in asymmetric synthesis to accelerate chemical reactions with controlled spatial structures. This compound is specifically designed to facilitate stereoselective reactions, making it an essential tool in organic chemistry laboratories. Its role is critical in achieving high enantiomeric purity, which is vital for producing compounds with specific biological activities. As a chiral catalyst, it enables chemists to direct reaction pathways with precision, reducing the need for additional purification steps.

The unique properties of TCI R0154 include its ability to selectively interact with substrates, enhancing reaction efficiency while maintaining stereochemical control. Its stability under specific conditions ensures consistent performance, making it a reliable choice for complex synthetic processes. The compound’s effectiveness in promoting asymmetric reactions is further enhanced by its compatibility with various reaction conditions, allowing for flexibility in experimental design. These characteristics make it a preferred option for researchers aiming to achieve high-quality, reproducible results.

In Indonesian laboratories, TCI R0154 is widely used in organic chemistry research, particularly in pharmaceutical and molecular synthesis applications. Its role in producing bioactive compounds supports advancements in drug development and industrial chemistry. The compound's versatility and reliability have made it a standard in academic and industrial settings, contributing to the growth of asymmetric catalysis research in the region.

TCI brochures (PDF)

Ruthenium Complex Catalysts for Asymmetric Hydrogenation of Olefins and Functionalized Ketones 2024-12-10 · p. 2
Hydrogenation Catalysts 2025-11-10 · p. 7

Related TCI products

Asymmetric Synthesis: TCI R0154 is ideal for asymmetric synthesis due to its ability to control stereochemistry and produce enantiomerically pure compounds.
Pharmaceutical Research: This catalyst is used in drug development to create compounds with high biological activity and specific spatial configurations.
Organic Chemistry Studies: It supports complex organic reactions where precise stereocontrol is required for the synthesis of target molecules.
Industrial Chemical Production: Its efficiency and selectivity make it suitable for large-scale synthesis of specialty chemicals and pharmaceutical intermediates.
Molecular Complexity Studies: TCI R0154 is employed in the synthesis of complex molecules, enabling researchers to explore new chemical structures and functionalities.

Brand	TCI
CAS number	944451-28-9
Molecular formula	—
Purity	—
Category	Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes	Available in various quantities as per standard laboratory supply
Physical form	Solid or powder, depending on manufacturer specifications
Storage	Store in a cool, dry place away from moisture and direct sunlight

TCI R0154 should be stored in a cool, dry environment to maintain its chemical stability and effectiveness. It is recommended to use airtight containers to prevent exposure to moisture and air, which could degrade its catalytic properties. Proper labeling of storage containers is essential for safe handling and easy identification. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when handling this material. It is important to ensure that the substance is kept away from incompatible materials and stored in a well-ventilated area. Regular monitoring of storage conditions will help maintain the integrity of the compound for optimal performance in chemical reactions.

References cited in the TCI brochure

Takao Saito. New Chiral Diphosphine Ligands Designed to have a Narrow Dihedral Angle in the Biaryl Backbone Advanced Synthesis & Catalysis, 2001. doi:10.1002/1615-4169(20010330)343:3<264::aid-adsc264>3.0.co;2-t