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TCI

CAS 944451-29-0

[RuCl(p-cymene)((S)-segphos(regR))]Cl TCI R0155

[RuCl(p-cymene)((S)-segphos(regR))]Cl TCI R0155

Chemical Identity

CAS No.
944451-29-0
PubChem
CID 51001217·SID 253662111
Formula
C48H42Cl2O4P2Ru
Molecular weight
916.8 g/mol
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
[4-(5-diphenylphosphanyl-1,3-benzodioxol-4-yl)-1,3-benzodioxol-5-yl]-diphenylphosphane;1-methyl-4-propan-2-ylbenzene;ruthenium(2+);dichloride
SMILES
CC1=CC=C(C=C1)C(C)C.C1OC2=C(O1)C(=C(C=C2)P(C3=CC=CC=C3)C4=CC=CC=C4)C5=C(C=CC6=C5OCO6)P(C7=CC=CC=C7)C8=CC=CC=C8.[Cl-].[Cl-].[Ru+2]
InChIKey
HZLSGDCLBWZKRB-UHFFFAOYSA-L
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TCI R0155 944451-29-0 is a chiral catalyst complex used in asymmetric synthesis, playing a crucial role in modern chemical laboratories. This compound is a complex of rhenium chloride, p-cymene, and the (S)-segphos ligand, designed to facilitate the formation of chiral compounds with high enantioselectivity. Its application is essential in organic chemistry, particularly in the development of pharmaceuticals and fine chemicals where stereochemistry is critical. The compound is widely used for its ability to catalyze reactions efficiently without being consumed in the process.

The material is preferred due to its high stability, excellent catalytic activity, and the ability to produce highly enantioselective products. Its chiral nature allows it to direct reactions toward specific stereoisomers, making it a valuable tool for chemists aiming for precise control over product stereochemistry. The compound is also versatile, suitable for various types of chemical reactions, and available in multiple packaging options, which makes it convenient for laboratory use. Its reliability and effectiveness have made it a standard in many research settings.

In Indonesian laboratories, this compound is extensively used in organic synthesis research, especially in asymmetric catalysis. It is a key component in the development of new drugs and specialty chemicals, where the ability to control stereochemistry is essential. Its high quality and consistent performance make it a preferred choice among researchers in the field of synthetic chemistry. The compound is commonly found in academic and industrial research facilities across Indonesia, supporting advanced chemical processes and innovation.

  • Asymmetric Synthesis: This catalyst is ideal for asymmetric synthesis due to its ability to produce chiral compounds with high enantioselectivity, making it suitable for pharmaceutical and fine chemical applications.
  • Organic Chemistry Research: It supports complex organic reactions by enabling the formation of specific stereoisomers, which is essential in the development of new chemical compounds.
  • Drug Development: The compound is used in the synthesis of chiral pharmaceuticals, where precise control over stereochemistry is critical for drug efficacy and safety.
  • Specialty Chemical Production: It is applied in the production of specialty chemicals that require controlled stereochemistry, such as agrochemicals and materials science compounds.
  • Academic Research: It is widely used in university and research institutions for teaching and experimental work in asymmetric catalysis and synthetic chemistry.

Brand TCI
CAS number 944451-29-0
Molecular formula —
Purity —
Category Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes Available in various packaging options suitable for laboratory use
Physical form —
Storage Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its stability and activity. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its performance. Due to its chemical nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. It is important to ensure that the storage area is well-ventilated to minimize any potential risks associated with its handling. Proper labeling and storage practices are essential to maintain the integrity of the compound and ensure safe laboratory operations.

References cited in the TCI brochure

  1. Takao Saito. New Chiral Diphosphine Ligands Designed to have a Narrow Dihedral Angle in the Biaryl Backbone Advanced Synthesis &amp; Catalysis, 2001. doi:10.1002/1615-4169(20010330)343:3<264::aid-adsc264>3.0.co;2-t