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CAS 1333981-84-2

(R,R)-Ts-DENEB(regR) TCI T3078

(R,R)-Ts-DENEB(regR) TCI T3078

Chemical Identity

CAS No.
1333981-84-2
PubChem
CID 91972070·SID 253659910
Formula
C31H33ClN2O3RuS
Molecular weight
650.2 g/mol
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
[(1R,2R)-2-[2-[(4-methylphenyl)methoxy]ethylamino]-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;ruthenium(2+);chloride
SMILES
CC1=CC=C(C=C1)COCCN[C@H](C2=CC=CC=C2)[C@@H](C3=CC=CC=C3)[N-]S(=O)(=O)C4=CC=C(C=C4)C.[Cl-].[Ru+2]
InChIKey
INKUCOHLIHBSDN-ZAMYOOMVSA-M
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(R,R)-Ts-DENEB(regR) (CAS 1333981-84-2) is a high-quality chemical from TCI, supplied as Reagent Grade.

Application: Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.

Specifications:

  • Molecular formula: C31H33ClN2O3RuS
  • CAS number: 1333981-84-2
  • TCI product code: T3078

Synonyms: Chloro[(R,R)-N-[2-[2-(4-methylbenzyloxy)ethyl]amino-1,2-diphenylethyl]-p-toluenesulfonamide]ruthenium(II); Chloro[(R,R)-N-[2-(4-methylbenzyloxy)ethyl]-N'-(p-toluenesulfonyl)-1,2-diphenylethylenediamine]ruthenium(II)

Available from AMI Scientific, the authorised TCI distributor in Indonesia. Contact us for pricing and stock availability — we ship throughout Indonesia.

Advantages (TCI brochure)

  • Reduces carbonyl groups selectively
  • Requires no high pressure equipment by using formic acid or IPA as a hydrogen source

From the TCI brochure

  • Asymmetric transfer hydrogenation of ketones

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Data from the TCI brochure

time3 h (substrate 1 (aryl methyl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% yield>99 (substrate 1 (aryl methyl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% ee98 (R) (substrate 1 (aryl methyl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
time5 h (substrate 2 (alpha-chloro aryl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% yield>99 (substrate 2 (alpha-chloro aryl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% ee97 (S) (substrate 2 (alpha-chloro aryl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
time5 h (substrate 3 (alpha-hydroxy aryl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% yield98 (substrate 3 (alpha-hydroxy aryl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% ee96 (S) (substrate 3 (alpha-hydroxy aryl ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
time5 h (substrate 4 (bicyclic chromanone-type ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% yield>99 (substrate 4 (bicyclic chromanone-type ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% ee>99 (R) (substrate 4 (bicyclic chromanone-type ketone), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
time5 h (substrate 5 (heteroaryl methyl ketone, furan type), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% yield>99 (substrate 5 (heteroaryl methyl ketone, furan type), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)
% ee98 (R) (substrate 5 (heteroaryl methyl ketone, furan type), 0.1 mol% T3078, Et3N, HCO2H, 60 ºC)

Source: TCI brochure RR034 (2026-01-30)

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References cited in the TCI brochure

  1. Taichiro Touge. Oxo-Tethered Ruthenium(II) Complex as a Bifunctional Catalyst for Asymmetric Transfer Hydrogenation and H2 Hydrogenation Journal of the American Chemical Society, 2011. doi:10.1021/ja207283t