Pathway diagram: xylemin inhibits thermospermine, which suppresses xylem differentiation; spermidine converts to thermospermine; photos of xylem with and without xylemin

Polyamine Xylemin Induces Xylem Differentiation with Synthetic Proauxin

Xylemin dihydrochloride (X0080) is a polyamine whose unique function was reported by Takahashi, Motose and co-workers.¹) It promotes xylem differentiation when co-treated with the synthetic proauxin 2,4-D IOE (O0518), acting by inhibiting thermospermine biosynthesis, which otherwise suppresses xylem differentiation. In cotyledons of Arabidopsis thaliana, the combination shows a synergistic effect on ectopic xylem differentiation, while application to the shoot apex of A. thaliana has a dwarfing effect. Xylemin is anticipated to be used in research and development of agrochemicals and biomass energy.

Pathway diagram: xylemin inhibits thermospermine, which suppresses xylem differentiation; spermidine converts to thermospermine; photos of xylem with and without xylemin
Source: TCI brochure LL071
Figure 1: cotyledons of Nicotiana benthamiana cleared after fixation, mock versus 2,4-D IOE + xylemin
Source: TCI brochure LL071

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References

  1. K. Yoshimoto, H. Takamura, I. Kadota, H. Motose, T. Takahashi, Sci. Rep. 2016, 6, 21487. doi:https://doi.org/10.1104/pp.104.055145
  2. Y. Kondo, H. Fukuda, et al., Nat. Commun. 2014, 5, 3504. doi:https://doi.org/10.1038/ncomms4504
  3. M. Yamaguchi, T. Demura, et al., Plant Physiol. 2010, 153, 906. doi:https://doi.org/10.1104/pp.110.154013
  4. S. Sawa, T. Demura, G. Horiguchi, M. Kubo, H. Fukuda, Plant Physiol. 2005, 137, 141. doi:https://doi.org/10.1104/pp.104.055145

Download TCI brochure Xylem Differentiation-Inducing Polyamine Xylemin (PDF)

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